中西医结合治疗高血压合并失眠30例临床观察

Clinical Observation on 30 Cases of Hypertension Complicated with Insomnia Treated with Integrated Traditional Chinese and Western Medicine

目的:观察中西医结合治疗高血压合并失眠的临床疗效、安全性及机理。方法:选取高血压60例,随机分为对照组和观察者各30例,两组均维持原降压方案,对照组采用酒石酸唑吡坦片治疗,观察组采用桂枝甘草龙骨牡蛎汤加减联合耳穴治疗,观察周期为4周,对两组血压情况、中医证候积分、睡眠质量指数评分及安全性指标等方面进行比较。结果:治疗后,观察组在脉压差、血压降幅、匹兹堡睡眠质量指数评分(PSQI),中医证候积分方面均优于对照组,差异均有统计学意义(P<0.05)。结论:中西医结合治疗可显著改善高血压合并失眠患者的睡眠质量,且有助于控制血压。

Objective To observe the clinical efficacy,safety and mechanism of integrated traditional Chinese and Western medicine in the treatment of hypertension complicated with insomnia.Methods 60 patients with hypertension were randomly divided into Control Group(n=30)and Observation Group(n=30).The control group was treated with Zolpidem tartrate,and the observation group was treated with Guizhi Gancao Longgu Muli decoction combined with auricular point therapy,the observation period was 4 weeks.The blood pressure,the score of TCM Syndrome,the score of sleep quality index and the index of safety were compared between the two groups.Results After treatment,the observation group in pulse pressure difference,blood pressure drop,Pittsburgh Sleep Quality Index Score(PSQI),tcm syndrome scores were better than the control group,the difference was statistically significant(p<0.05).Conclusion Integrated Traditional Chinese and Western medicine can significantly improve the sleep quality of patients with hypertension and insomnia,and help to control blood pressure.