膝内侧半月板根部撕裂修复与切除的荟萃分析

Meniscus repair versus meniscectomy for medial meniscus posterior root tears of the knee:a meta-analysis

[目的]汇集已发表文献中的数据,比较修复术与切除术治疗膝内侧半月板根部撕裂(medial meniscus posterior root tears,MMPRT)的临床效果。[方法]检索建库至2020年10月,PubMed、Cochrane图书馆、Web of Science及中国知网(CNKI)、万方医学、维普数据库中关于MMPRT修复术与部分切除术比较的文献,由两名研究员标准筛选、数据提取、质量评估。采用Review Manager 5.4软件进行荟萃分析。[结果]纳人6项研究,共263例患者,其中修复术149例,部分切除术114例。荟萃分析表明,在Lysholm评分(MD=9.72,95%CI 3.27-16.16,P=0.003)、IKDC评分(MD=11.91,95%CI 1.21-22.61,P=0.03)、Kellgren-Lawrence等级(OR=0.09,95%CI 0.04-0.21,P<0.001)和行全膝关节置换术(OR=0.10,95%CI 0.04-0.24,P<0.001)方面,修复术均优于切除术。[结论]对于MMPRT的治疗,修复术在临床评分及长期预后方面均明显优于切除术。

[Objective]To compare the eclinical outcomes of meniseus repair versus meniscectomy for medial meniscus posterior root tears(MMPRT)by summarizing data from the published literatures.[Methods]The articles regarding comparison of meniscus repair with meniscectomy for MMPRT were retrieved from data bases,such as PubMed,Cochrane Library,Web of Science,CNKI,w anfang Medical,and W eipu databases from the establishment to October 2020.After screening,data extraction,and quality evaluation were finished by two.researchers,a meta-analysis was conducted by using Review Manager 5.4 software.[Results]A total of 6 papers were enrolled into this;study,involving 263 patients,including 149 cases of meniscus repair and 114 cases of partial meniscectomy.As results of meta-analysis,meniscus repair proved sinificanly superior to the meniscectomy in terms of Lysholm score(MD=9.72,95%CI 3.27-16.16,P=0.003).IK-DC score(MD=11.91,95%CI 1.21-22.61,P=0.03),Kellgren-Lawrence grade(0R=0.09,95%CI 0.04-0.21,P<0.001),and total knee ar-throplasty(OR=0.10,95%CI 0.04-0.24,P<0.001).[Conclusion]For the treatment of MMPRT,meniscus repair is significantly better than the meniscectomy regarding to clinical scores and long-term prognosis in this study.