超声引导射频消融治疗腹膜后肿瘤的临床价值

Clinical value of ultrasound-guided radiofrequency ablation in the treatment of retroperitoneal tumors

目的探讨超声引导射频消融治疗腹膜后肿瘤的临床价值。方法回顾性分析2018年1月至2020年1月郑州大学第一附属医院行超声引导下射频消融治疗的13例腹膜后肿瘤患者的临床资料,评价消融疗效,观察术后并发症,比较射频消融治疗前后肿瘤体积变化。结果射频消融术后患者疼痛、消化不良等症状均明显改善,住院时间为(9.2±2.9)d。10例患者肿瘤完全消融,1例肿瘤残留,2例肿瘤转移。1例患者术后十二指肠穿孔并发腹腔内感染,其余患者未出现严重并发症。13例患者共20个病灶,术前及术后1、3、6个月最大径分别为(39.5±15.9)mm、(30.6±4.9)mm、(15.6±7.7)mm和(9.9±3.1)mm,术后1、3、6个月均小于术前(均P<0.05)。结论超声引导下射频消融是一种实时、精准、安全有效、并发症少的微创治疗手段,对于腹膜后肿瘤具有较高的临床应用价值。

Objective To explore the clinical value of ultrasound-guided radiofrequency ablation in the treatment of retroperitoneal tumors.Methods The clinical data of 13 patients with retroperitoneal tumors treated with ultrasound-guided radiofrequency ablation in the First Affiliated Hospital of Zhengzhou University from January 2018 to January 2020 were analyzed retrospectively.The ablation effect was evaluated and the postoperative complications were observed.The changes of tumor volume before and after radiofrequency ablation were compared.Results The symptoms of pain and dyspepsia were significantly improved after radiofrequency ablation,and the hospital stay was(9.2±2.9)days.The tumor was ablated completely in 10 cases,tumor residual in 1 case and tumor metastasis in 2 cases.One patient had postoperative duodenal perforation complicated with intra-abdominal infection,and no serious complications occurred in other patients.There were 20 lesions in 13 patients.The maximum diameter of 20 lesions before operation and 1,3,6 months after operation were(39.5±15.9)mm,(30.6±4.9)mm,(15.6±7.7)mm and(9.9±3.1)mm,respectively,the maximum diameters of 1,3 and 6 months after operation were smaller than that before operation(P<0.05).Conclusion Ultrasound-guided radiofrequency ablation is a real-time,accurate,safe and effective minimally invasive treatment with few complications,and has a high clinical value for retroperitoneal tumors.