贵州省2020-2021年流感季6月龄-5岁儿童流感疫苗接种率与社会经济指标的双变量空间自相关分析

Bivariate spatial autocorrelation analysis of influenza vaccine coverage among children aged 6 months to 5 years during the 2020-2021 influenza season and socio-economic indicators in Guizhou province

目的分析社会经济水平对儿童流感疫苗(Influenza vaccine,InfV)接种率的影响。方法通过贵州省免疫规划信息管理系统收集2020-2021年流感季6月龄-5岁儿童InfV接种数据,采用双变量空间自相关分析以区县级为单位的儿童InfV接种率与国内生产总值(GDP)、人均GDP和人均可支配收入的空间相关性。结果贵州省2020-2021年流感流行季6月龄-5岁儿童InfV接种率为16.27%,各县区在1.01%-47.17%之间。双变量空间自相关分析显示,儿童InfV接种率与GDP、人均GDP和人均可支配收入均呈空间正相关,Moran’s I分别为0.195、0.242和0.272。双变量局部空间自相关分析显示,儿童InfV接种率与GDP、人均GDP和人均可支配收入分别存在29个、28个和33个聚集县区,共同存在11个聚集县区,包括8个高-高、2个低-低和1个高-低聚集县区。结论贵州省6月龄-5岁儿童InfV接种率低,社会经济水平显著影响儿童InfV接种率;需关注经济欠发达地区的儿童InfV接种。

Objective To analyze the association of socio-economic level on influenza vaccine(InfV) coverage in children.Methods We obtained data on influenza vaccination of children aged 6 months to 5 years in Guizhou province during the 2020-2021 influenza season from the Guizhou Immunization Information Management System. We determined the spatial autocorrelation of InfV coverage with gross domestic product(GDP), per capita GDP, and per capita disposable income using bivariate spatial autocorrelation analysis.Results InfV coverage was 16.27% among children aged 6 months to 5 years in Guizhou. Coverage levels by county/district ranged 1.01% to 47.17%. Bivariate spatial autocorrelation analysis showed that InfV coverage was positively correlated with GDP, per capita GDP, and per capita disposable income in spatial distribution, with Moran’s I values being 0.195, 0.242, and 0.272, respectively. Bivariate local spatial autocorrelation analysis showed 29, 28, and 33 clustering counties/districts associating InfV coverage with GDP, per capita GDP, and per capita disposable income, as well as 11 common clusters including 8 high-high, 2 low-low, and 1 high-low cluster.Conclusions InfV coverage was low among children aged 6 months to 5 years in Guizhou, and socio-economic level significantly influenced InfV coverage. We should pay attention to InfV vaccination for children in less-developed areas.