加味葛红汤治疗血瘀脉络型2型糖尿病合并冠心病心绞痛的临床观察

Clinical Observation of Jiawei Gehong Decoction in Treating Blood Stasis Vessel Type 2 Diabetes with Coronary Heart Disease and Angina Pectoris

目的探讨加味葛红汤治疗血瘀脉络型2型糖尿病合并冠心病心绞痛的应用效果。方法选取2020年1月至2021年6月在我院就诊的2型糖尿病合并冠心病心绞痛66例,随机分组,即对照组、治疗组(n=33)。对照组患者予以常规治疗,治疗组在对照组的基础上予以加味葛红汤治疗。观察两组心绞痛疗效、心电图疗效、空腹血糖(FPG)、餐后2h血糖(2h PBG)、糖化血红蛋白(Hb A1c)、总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)水平以及不良反应发生率。结果与对照组比较,治疗组心绞痛有效率90.91%、心电图有效率84.85%、HDL-C水平均明显更高P<0.05;且FPG、2h PBG、Hb A1c水平均明显更低。两组患者不良反应发生率比较,P<0.05。结论加味葛红汤能够明显改善血瘀脉络型2型糖尿病合并冠心病心绞痛患者血糖、血脂水平,显著提高疗效。

Objective To explore the effect of Jiawei Gehong Decoction in the treatment of blood stasis and vein-collateral type 2 diabetes with coronary heart disease and angina pectoris.Methods A total of 66 patients with type 2 diabetes and coronary heart disease and angina pectoris who were treated in our hospital from January 2020 to June 2021 were selected and grouped by random number table,namely the control group and the treatment group,with 33 cases in each.Patients in the control group were given conventional treatment,and the treatment group was treated with Jiawei Gehong Decoction on the basis of the control group.The efficacy of angina pectoris,ECG efficacy,FPG,2 h PBG,Hb A1 c levels,TC,TG,LDL-C,HDL-C levels and the incidence of adverse reactions were observed in the two groups.Results Compared with the control group,the effective rate of angina in the treatment group was 90.91%,the effective rate of ECG was 84.85%,the HDL-C level was significantly higher,P<0.05;and the FPG,2 h PBG,and Hb A1 c levels were significantly lower.The incidence of adverse reactions between the two groups of patients was compared,P<0.05.Conclusion Jiawei Gehong Decoction can significantly improve blood glucose and blood lipid levels in patients with blood stasis and vein-collateral type 2 diabetes combined with coronary heart disease and angina pectoris,and significantly improve the curative effect.