梅花针联合镵针治疗轻中度寻常型痤疮临床疗效观察

Effects of plum blossom needle combined with Chanzhen on mild to moderate acne vulgaris

目的:观察梅花针联合镵针治疗轻中度寻常型痤疮的临床疗效及对血清肿瘤坏死因子-α(TNF-α)和白介素-1α(IL-1α)的影响。方法:将48例轻中度寻常型痤疮患者随机分为梅花针联合镵针组(治疗组)和毫针组(对照组),各24例。梅花针联合镵针组采用梅花针弹叩刺皮损区、皮损周围区,并行鑱针轻划耳廓敏感区,每周1次,共4周;毫针组行局部围刺法和体针常规取穴法,每周2次,共4周。统计治疗前后两组患者的皮损积分、临床疗效、复发情况,检测血清TNF-α和IL-1α的表达水平。结果:两组皮损积分、愈显率、复发率、血清TNF-α及IL-1α含量比较,差异有统计学意义(P<0.05),梅花镵针组优于毫针组。结论:梅花针配合镵针能显著降低血清TNF-α和IL-1α含量,抑制炎症水平,在治疗轻中度寻常型痤疮上比毫针常规针刺具有优势。

Objective:To observe the clinical efficacy of plum blossom needle combined with Chanzhen on mild to moderate acne vulgaris,as well as its effect on serum tumor necrosis factor-α(TNF-α)and interleukin-1α(IL-1α).Methods:Forty-eight patients with mild to moderate acne vulgaris were randomly divided into plum blossom needle combined with Chazhen group(treatment group)and filiform needle group(control group),24 cases in each group.The treatment group was treated with plum blossom needle tapping the lesion area and its surrounding area and Chanzhen gently scratching the sensitive area of the auricle once a week for 4 weeks,while the control group was treated with local circumferential acupuncture and routine acupoint selection of body acupuncture,twice a week for 4 weeks.The skin lesion score,clinical curative effect and recurrence rate of two groups before and after treatment were observed and compared,and the expression levels of serum TNF-αand IL-1αwere detected.Results:In respects of skin lesion score and efficacy,the comparison with two groups have statistically significant(P<0.05),the treatment group was better than those of control group.After treatment,the expression levels of serum TNF-αand IL-1αof both groups were declined obviously,and had statistical difference between the two groups(P<0.05).Conclusion:Plum blossom needle combined with Chanzhen could significantly reduce serum TNF-αand IL-1αlevels,inhibit the level of inflammation,has more advantage in the treatment of mild to moderate acne vulgaris than filiform needle.