长链非编码RNA肺腺癌相关转录物1在乳腺癌中的研究进展

Progress of long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1 in breast cancer

乳腺癌的发生、发展是一个复杂的过程,多种生物活性物质参与其中。作为一种长链非编码RNA,肺腺癌相关转录物1(MALAT1)不仅在乳腺癌发生中的多个位点发挥作用,而且在乳腺癌患者治疗及预后评估中也发挥重要作用。文章就MALAT1在乳腺癌中的研究进展进行综述。

The occurrence and development of breast cancer is a complicated process,in which many kinds of bioactive substances are involved.As a long non-coding RNA,metastasis-associated lung adenocarcinoma transcript 1(MALAT1)not only plays a role in multiple sites of breast cancer,but also plays an important role in the treatment and prognosis evaluation of breast cancer patients.This article reviews the research progress of MALAT1 in breast cancer.