心力衰竭中医临床研究结局指标的研究进展

Research progress on outcome indicators of traditional Chinese medicine clinical research on heart failure

心力衰竭是多种心血管疾病的终末期阶段,是一组复杂的临床综合征。中医药在心力衰竭领域开展了一系列临床研究,围绕慢性心力衰竭的病理过程,主要采用的结局指标有心血管不良事件、生物标志物、心脏结构和功能、运动耐量、生活质量、临床症状等。中医临床研究中应根据干预措施、研究类型等充分评估所应用的结局指标,以期科学客观地突显干预措施的疗效。

Heart failure,as a group of complex clinical syndromes,is the end stage of a variety of cardiovascular diseases.Traditional Chinese medicine has carried out a series of clinical studies in the field of heart failure.The main outcome indicators are cardiovascular adverse events,biomarkers,cardiac structure and function,exercise tolerance,quality of life,clinical symptoms and so on in the clinical researches of traditional Chinese medicine.In TCM clinical research,the outcome indicators used should be fully evaluated according to the intervention measures,research types,etc.,so as to highlight the efficacy of intervention measures scientifically and objectively.