斯氏放线棒菌研究现状

Research status of Actinotignum schaalii

斯氏放线棒菌为兼性厌氧革兰阳性杆菌,随着实验室培养条件的完善和基质辅助激光解吸电离飞行时间质谱(MALDI-TOF MS)的广泛应用,检出率不断升高,其与泌尿系感染密切相关,对常用于治疗泌尿系感染的抗菌药物,如复方磺胺甲噁唑、喹诺酮类抗菌药物不敏感,对β-内酰胺类抗菌药物敏感。斯氏放线棒菌为新型尿路感染病原体,目前中国尚未见报道。为更好地了解斯氏放线棒菌,文章对斯氏放线棒菌的研究现状进行综述。

Actinotignum schaalii is facultative anaerobic Gram-positive Actinobacillus.With the improvement of clinical laboratory culture conditions and the wide usage of matrix-assisted laser desorption ionization time-of-flight mass spectrometry(MALDI-TOF MS),the detection rate of Actinotignum schaalii is increasing,and it is found that it is closely related to urinary tract infection.It is not sensitive to antibiotics commonly used,such as co-trimoxazole and quinolone,in the treatment of urinary tract infection,and it is sensitive to beta-lactamase.Actinotignum schaalii is a novel pathogen of urinary tract infection,and there has been no report on Actinotignum schaalii in China.In order to better understand Actinotignum schaalii,this review summarizes and expounds relevant reports abroad.