防治芹菜上重要害虫的替代药剂筛选及其膳食暴露风险评估

Screening and dietary intake risk assessment of alterative insecticides for Apium graveolens var.dulce

为了筛选防治芹菜上重要害虫的替代药剂,在上海市及银川市开展5%吡虫啉颗粒剂、0.5%阿维菌素颗粒剂及5%氯虫苯甲酰胺悬浮剂在芹菜上的田间试验,通过液相色谱-串联质谱法检测3种农药在芹菜上的残留量,并分别对3种农药进行膳食暴露风险评估。结果表明,5%吡虫啉颗粒剂、0.5%阿维菌素颗粒剂及5%氯虫苯甲酰胺悬浮剂分别以推荐剂量施用于芹菜后,收获期吡虫啉及阿维菌素在芹菜上最大残留量分别为0.97 mg/kg及0.01 mg/kg,氯虫苯甲酰胺安全间隔期内(1 d)在芹菜上的最大残留量为5.24 mg/kg,均低于其在芹菜上的最大残留限量值。中国居民摄入吡虫啉、阿维菌素、氯虫苯甲酰胺的慢性暴露风险(%ADI)最大值为5.17%,急性暴露风险(%ARfD)最大值为11.20%,均远低于100%,膳食暴露风险低。结果表明吡虫啉、阿维菌素、氯虫苯甲酰胺可替代高毒农药用于芹菜上关键虫害的防治。

The objective of this study was to discover alterative insecticides for celery(Apium graveolens var.dulce).Residue experiments of imidacloprid 5%GR,abamectin 0.5%GR and chlorantraniliprole 5%SC in celery were carried out in Shanghai and Yinchuan.The ultra-high performance liquid chromatography-tandem mass spectrum(UPLC-MS/MS)was used to determine the residues of these insecticides in celery.Dietary intake risk assessments were performed.Field experiments showed that the final maximal residues of imidacloprid 5%GR,abamectin 0.5%GR and chlorantraniliprole 5%SC in celery collected at safe intervals were 0.97 mg/kg,0.01 mg/kg,and 5.24 mg/kg respectively,when they were applied at their recommended dosages.All of the final concentrations were below their maximum residue limits in celery.The risk assessments showed that the maximum value of%ADI of imidacloprid,abamectin and chlorantraniliprole was 5.17%,and that of%ARfD was 11.2%,which were far below 100%with a low exposure risk.Therefore,imidacloprid,abamectin and chlorantraniliprole were applicable as alterative insecticides for celery.