结肠癌治疗研究进展

Research advances in the treatment of colon cancer

结肠癌是最常见的癌症相关死亡原因,在不同的癌症相关死亡中仅次于肺癌。结肠癌的治疗取决于多种因素,包括结肠癌的性质(散发性或遗传性)、分子因素、年龄、结肠癌分期等。目前的治疗方法有手术/息肉切除、化疗、放疗、联合治疗、免疫治疗等;先进的治疗方法有基因治疗、细胞治疗、靶向免疫治疗等,目前还处于研发阶段。然而,每种治疗方案都有副作用,而且每种疗法都有缺点,如肿瘤复发、靶点缺乏特异性以及抗癌药物的耐药性等。因此,对结肠癌治疗方法的研究值得探索。虽然结肠癌治疗已经达到了较高的水平,但更多的学者和研究者及临床医生仍在继续为研发更好的结肠癌治疗方法而努力。

Colon cancer is the most common cause of death from cancer,which is second only to lung cancer.The treatment of colon cancer depends on multifarious factors,including the nature(sporadic or hereditary),molecular factors,age,stage of colon cancer,etc.Current treatment includes surgery/polypectomy,chemotherapy,radiotherapy,combined therapy,and immunotherapy.The advanced treatment methods consist of gene therapy,cell therapy,and targeted immunotherapy,which are still under research and development.Nevertheless,each treatment has side effects,and every therapy has its drawbacks such as tumor recurrence,lack of target specificity,and resistance to anticancer drugs.Therefore,it is worthy of exploring the treatment for colon cancer.Although relatively high level has been reached in the treatment of colon cancer,more scholars,researchers and clinicians continue to work to develop better colon cancer treatments.