摘要
目的掌握青海省人间布鲁氏菌病(简称布病)流行趋势,为科学防治布病提供依据。方法2019、2020年,在青海省的国家级和省级布病监测点,共18个县(市、区,简称县),每年每个县抽检常住职业人群血清样本不少于400份,进行布病虎红平板凝集试验(RBPT)和试管凝集试验(SAT),按《布鲁氏菌病诊断》(WS 269-2019)标准进行检测和判定。结果2019年国家级布病监测点共监测1612人,检出RBPT阳性93人、SAT阳性54人,确诊患病人数54人,患病率为3.35%(54/1612);2020年国家级布病监测点共监测1677人,检出RBPT阳性151人、SAT阳性80人,确诊患病人数80人,患病率为4.77%(80/1677)。不同年份间国家级布病监测点RBPT阳性率、SAT阳性率及患病率比较,差异均有统计学意义(χ^(2)=12.52、4.24、4.24,P均<0.05)。2019年省级布病监测点共监测6043人,检出RBPT阳性128人、SAT阳性91人,确诊患病人数87人,患病率为1.44%(87/6043);2020年省级布病监测点共监测5664人,检出RBPT阳性108人、SAT阳性59人,确诊患病人数52人,患病率为0.92%(52/5664)。不同年份间省级布病监测点RBPT阳性率比较,差异无统计学意义(χ^(2)=0.66,P=0.416),而SAT阳性率及患病率比较,差异均有统计学意义(χ^(2)=4.98、14.57,P均<0.05)。结论2019和2020年青海省国家级与省级布病监测点均有人间布病病情。
Objective To master the epidemic trend of human brucellosis in Qinghai Province,so as to provide basis for scientific prevention and control of the disease.Methods In 2019 and 2020,at the national and provincial brucellosis monitoring sites in Qinghai Province,a total of 18 counties(cities and districts,hereinafter referred to as counties),no less than 400 serum samples were sampled every year for brucellosis Rose-Bengal plate agglutination test(RBPT)and serum tube agglutination test(SAT),which would be tested and judged according to the criteria of"Diagnosis for Brucellosis"(WS 269-2019).Results In 2019,a total of 1612 people were monitored in national brucellosis monitoring sites,93 were RBPT positive,54 were SAT positive,54 were diagnosed,and the prevalence rate was 3.35%(54/1612).In 2020,1677 people were monitored in national brucellosis monitoring sites,151 were RBPT positive,80 were SAT positive,80 were diagnosed,and the prevalence rate was 4.77%(80/1677).There were significant differences in RBPT positive rate,SAT positive rate and prevalence rate among national monitoring sites between the two years(χ^(2)=12.52,4.24,4.24,P<0.05).In 2019,a total of 6043 people were monitored in provincial brucellosis monitoring sites,128 were RBPT positive,91 were SAT positive,87 were diagnosed,and the prevalence rate was 1.44%(87/6043).In 2020,5664 people were monitored,108 were RBPT positive,59 were SAT positive,52 were diagnosed,and the prevalence rate was 0.92%(52/5664).There was no significant difference in RBPT positive rate among provincial monitoring sites between the two years(χ^(2)=0.66,P=0.416),and the differences in SAT positive rate and prevalence rate were statistically significant among provincial monitoring sites between the two years(χ^(2)=4.98,14.57,P<0.05).Conclusion In 2019 and 2020,there are human brucellosis in national and provincial brucellosis monitoring sites in Qinghai Province.
作者
赵志军
李强
李积权
王建玲
马丽
薛红梅
时雨
樊迪
秦豫民
赵元博
田广
徐立青
Zhao Zhijun;Li Qiang;Li Jiquan;Wang Jianling;Ma Li;Xue Hongmei;Shi Yu;Fan Di;Qin Yumin;Zhao Yuanbo;Tian Guang;Xu Liqing(Department of Brucellosis Prevention and Control,Qinghai Institute for Endemic Disease Prevention and Control,Xining 810021;Graduate School,Qinghai University,Xining 810010)
出处
《中华地方病学杂志》
CAS
北大核心
2022年第3期200-203,共4页
Chinese Journal of Endemiology
基金
国家自然科学基金(81860588)。