基于脾主升津理论观察Hp感染对干眼症的影响

Observation on the Effect of Hp Infection on Dry Eye Disease Based on the Theory of Spleen Governing Ascending Body Fluid

目的观察Hp感染对干眼症相关参数的影响。方法对100例Hp感染患者根除前后的OSDI评分、Schirmer I、BUT、TMH、NI-BUTf、睑板腺评分、眼红指数等指标进行对比分析。结果Hp根除前干眼症总患病率为59%,Hp根除后,干眼症总患病率为37%,Hp根除前后干眼症总患病率差异有统计学意义(P<0.05);Hp根除后患者OSDI评分显著下降,与Hp根除前对比差异有明显统计学意义(P<0.01);Hp根除后患者Schirmer I数值显著增加,与Hp根除前对比差异有明显统计学意义(P<0.01),BUT较Hp根除前差异无统计学意义(P>0.05);Hp根除后患者TMH显著增加,眼红评分显著下降,与Hp根除前对比差异均有明显统计学意义(均P<0.01),NI-BUT、睑板腺评分较Hp根除前均差异无统计学意义(均P>0.05)。结论Hp感染对干眼症存在明显影响。

Objective To observe the effect of Hp infection on dry eye related parameters.Methods The OSDI score,Schirmer I,BUT,TMH,NI-BUTf,meibomian gland score and eye red index of 100 patients with Hp infection before and after eradication were compared and analyzed.Results The total prevalence of dry eye disease before Hp eradication was 59%.After Hp eradication,the total prevalence of dry eye disease was 37%.Hp the total prevalence of dry eye disease before and after eradication was statistically different(P<0.05).The OSDI score of patients after Hp eradication decreased significantly compared with that before Hp eradication(P<0.01).The Schirmer I value of patients after Hp eradication increased significantly(P<0.01),compared with that before Hp eradication(P>0.05).The TMH of the patients after Hp eradication increased significantly,the eye red score decreased significantly compared with the Hp before eradication(all P<0.01),the meibomian gland score was no significant difference compared with Hp before eradication(all P>0.05).Conclusion Hp infection has obvious effect on dry eye.