细胞凋亡及其与肌纤维的关联机制研究进展

Research Progress of Apoptosis and Its Correlation Mechanism with Muscle Fibers

细胞凋亡是机体内细胞的主动、程序性的死亡过程,对于保持细胞内环境稳态至关重要。研究表明,细胞凋亡参与畜禽的宰后成熟过程,且不同类型肌纤维的凋亡进程和速率存在较大差异。因此,本文将从细胞凋亡概念、细胞凋亡路径、细胞凋亡对宰后成熟过程的影响、控制宰后成熟过程中细胞凋亡的方法等方面进行综述,最终将细胞凋亡与肌纤维特性联系起来,深入探讨细胞凋亡与肌纤维的关联机制,为控制宰后不同部位肌肉的成熟过程提供参考依据。

Apoptosis is an active and procedural death process of cells in the body,which is essential to maintain the homeostasis of intracellular environment. Studies have shown that apoptosis is involved in the postmortem aging process of livestock and poultry,and the apoptosis process and rate of different types of muscle fibers are quite different. Therefore,the apoptosis concept,apoptosis pathway,the effect of apoptosis on the postmortem aging process and the methods for controlling apoptosis in the postmortem maturation process were reviewed in this study. Finally,the apoptosis is related to the characteristics of muscle fibers,and the association mechanism between apoptosis and muscle fibers is deeply explored to provide a theoretical basis for controlling the aging process of different parts of the muscle.[Chinese Journal of Animal Nutrition,2022,34(5):2847-2855]