内蒙古地区成人心血管疾病发病风险评估

Risk assessment of cardiovascular diseases in adults in inner Mongolia

目的评估内蒙古地区居民动脉粥样硬化性心血管疾病(atherosclerotic cardiovascular disease,ASCVD)的发病风险。方法利用国家2015年“心血管病高危人群早期筛查与综合干预项目”建立的人群,依据《中国成人血脂异常防治指南(2016年修订版)》方法进行ASCVD 10年发病风险和余生风险评估。结果65406名研究对象ASCVD l0年发病风险为极高危、高危、中危和低危的比例分别为4.8%、29.0%、27.8%和38.4%,将极高危和高危进行合并定义为本研究的高危,其高危率为33.8%,经2010年全国人口年龄标化,ASCVD l0年发病风险高危率为28.4%。男性ASCVD 10年发病风险高危率高于女性,吸烟人群高于不吸烟人群,且随年龄增长呈现上升趋势(P<0.01)。ASCVD 10年发病风险为中危且年龄<55岁的5089例研究对象再进行余生风险评估,其中高危者2063例(比例为40.5%)。结论内蒙古地区ASCVD10年发病风险高危率较高;余生风险评估为高危的比例高于全国其他地区,对于内蒙古地区应制定相应防治策略,尤其要关注中青年人群的余生发病风险。

Objective To assess the risk of atherosclerotic cardiovascular disease(ASCVD)among residents in Inner Mongolia.Methods The10-year risk of ASCVD and the residual risk of ASCVD were assessed according to the Chinese Guidelines for Prevention and Treatment of Adults with Dyslipidemia(Revised Edition 2016)in the population established by the 2015 National Program of Early Screening and Comprehensive Intervention for High-Risk People with Cardiovascular Diseases.Results The extremely high-risk,high-risk,medium-risk and low-risk rate of 10-year of ASCVD in65406 individuals were 4.8%,29.0%,27.8%and 38.4%,respectively.The combination of extremely high-risk and high-risk was defined as the high-risk in this study,and the high-risk rate of ASCVD was 33.8%.According to 2010 China census,the age-standardized rate of l0-year highrisk of ASCVD was 28.4%.The l0-year high-risk rate of ASCVD among male participants was higher than that among female participants,and that of smoking people was higher than that of nonsmoking people.Moreover,an upward trend with age was showed(P<0.01).A total of 5089participants with 10-year medium-risk of ASCVD and age<55 years old were assessed for their residual risk,of which 2063 participants(40.5%)were assessed as high-risk.Conclusions In Inner Mongolia,10-year high-risk rate of ASCVD is high.The high-risk rate of residual risk is higher than that in other areas in China.In Inner Mongolia,some suitable prevention and control strategies should be developed,especially focusing on the residual risk of ASCVD among the young and middle-aged population.