睑板腺按摩配合Croma角膜保护剂治疗白内障超声乳化术后干眼的效果

Effects of meibomian gland massage combined with Croma corneal protector on dry eyes after phacoemulsification for cataract

目的探讨睑板腺按摩配合Croma角膜保护剂治疗白内障超声乳化术后干眼的效果。方法按照随机数字表法将广东省佛山市第一人民医院2018年10月至2020年4月收治的白内障超声乳化术后干眼患者82例分为研究组与对照组,每组各41例。对照组采取睑板腺按摩,研究组在对照组基础上加用Croma角膜保护剂,均治疗2周。比较两组临床疗效、治疗前后干眼情况相关指标、疾病缓解情况、不良事件发生率。结果治疗后,研究组总有效率高于对照组(P<0.05);两组泪膜客观散射指数(OSI)、角膜荧光素染色(CFL)、眼表体征、感觉性症状评分较治疗前降低,且研究组OSI、CFL、眼表体征、感觉性症状评分低于对照组(P<0.05);两组Schirmer I试验(SIt)数值较治疗前升高,且研究组SIt数值高于对照组(P<0.05);两组不良事件发生率比较,差异无统计学意义(P>0.05)。结论睑板腺按摩及Croma角膜保护剂能够有效预防白内障超声乳化术后干眼症状,疗效确切,安全性高。

Objective To investigate the effects of meibomian gland massage combined with Croma corneal protector in the treatment of dry eye after phacoemulsification.Methods According to the random number table method,82 patients with dry eye after phacoemulsification in Foshan First People’s Hospital from October 2018 to April 2020 were divided into study group and control group,with 41 cases in each group.The control group was treated with meibomian gland massage,and the study group was treated with Croma corneal protector in addition to the control group,all were treated for two weeks.The clinical efficacy,dry eye before and after treatment,disease remission and incidence of adverse events were compared between the two groups.Results After treatment,the total effective rate of study group was higher than that of control group(P<0.05);the objective scattering index(OSI),corneal fluorescein staining(CFL),ocular surface signs,and sensory symptom scores of the two groups were lower than those before treatment,and the OSI,CFL,ocular surface signs and sensory symptom scores of study group were lower than those of control group(P<0.05);the Schirmer I test(SIt)value in two groups was higher than that before treatment,and the SIt value in study group was higher than that in control group(P<0.05);there was no significant difference in the incidence of adverse events between two groups(P>0.05).Conclusion Meibomian gland massage and Croma corneal protector can effectively prevent dry eye symptoms after phacoemulsification with definite curative effect and high safety.