细菌性传染病实验室病原学监测预警技术发展及其应用

Advance on research and application of laboratory pathogen monitoring and early warning technology of bacterial infectious diseases

人类目前依然面临着细菌性传染病带来的公共卫生挑战。开展系统的传染病监测预警是预防和控制传染病最直接的手段。病原学是传染病监测预警的重要组成部分。敏感准确的病原学监测可以在第一时间识别病原、识别暴发、识别来源。本研究对细菌性传染病的病原学监测预警技术研究和应用现状进行综述,总结病原学在传染病监测预警中的重要性和应用场景以及病原学监测预警技术研究进展,并在我国现有的国家致病菌识别网等实验室监测网络的工作基础上,提出了传染病实验室网络化监测发展趋势和展望,为建立健全传染病监测预警体系提供参考。

Human beings are still facing the public health challenges from bacterial infectious diseases.Carrying out systematic infectious disease monitoring and early warning is the most direct solution to prevent and control infectious diseases.Etiology is an important part of infectious disease monitoring and early warning.Effective pathogen monitoring can identify pathogens,outbreaks and sources at the first time.In this study,we have reviewed the research and application of etiology monitoring and early warning technology of bacterial infectious diseases and summarized the importance and application scenarios of etiology in infectious disease monitoring and early warning,as well as the research progress of etiology monitoring and early warning technology.Based on the work of existing laboratory monitoring networks,such as Chinese Pathogen Identification Network,the development trend and prospect of infectious disease laboratory network monitoring are put forward to provide a reference for establishing and perfecting the infectious disease monitoring and early warning system.