摘要
The first total synthesis of dracaenins A and B is achieved in four steps.The synthesis features the conver-gent coupling of three readily available fragments with minimized use of protecting groups.The chemical synthesis enables the discovery of their activity in stimulating platelet aggregation,and thus,sheds light on the possible origin of the hemostatic effect of dragon’s blood.
基金
supported by the National Natural Science Foun-dation of China(No.21871161)
Key Project at Central Government Level for the Ability Establishment of Sustainable Use for Valu-able Chinese Medicine Resources(No.2060302)
Postgraduate Research&Practice Innovation Program of Jiangsu Province(No.KYCX19_1256).
