经颅直流电刺激治疗脑卒中后功能障碍的研究进展

Research progress of transcranial direct current stimulation for post-stroke dysfunction

经颅直流电刺激(transcranial direct current stimulation,t DCS)是利用恒定的低强度直流电(1~2 mA)调节大脑皮质神经元活动的非侵入性技术。近年来,tDCS作为探索人类大脑功能和治疗各种神经疾病的工具,受到越来越广泛的关注,但是tDCS治疗脑卒中后功能障碍这一领域,目前仍缺乏系统且全方位的总结。该文通过对tDCS治疗脑卒中后功能障碍进行阐述,综合近年来相关的基础研究和临床研究,总结并探讨tDCS治疗脑卒中后功能障碍的理论机制与应用效果,从而为更深层次的研究提供依据。

Transcranial direct current stimulation(tDCS) is a non-invasive technique that uses constant lowintensity direct current(1 to 2 mA) to regulate neuronal activity in the cerebral cortex.In recent years,tDCS has received more and more attention as a tool to explore human brain function and treat various neurological diseases.However,there is still a lack of systematic and comprehensive reviews in the tDCS treatment of post-stroke dysfunction.This article reviews the treatment of post-stroke dysfunction with tDCS,integrates relevant basic research and clinical research in recent years,summarizes and discusses the theoretical mechanism and application effect of tDCS in the treatment of poststroke dysfunction,so as to provide a basis for further research.