终末期肾病相关性肾细胞癌的研究进展

Research progress of end-stage renal disease complicated with renal cell carcinoma

控制终末期肾病患病率和病死率的上升是我国慢性病防治的重点。发生终末期肾病相关性肾细胞癌是终末期肾病患者死亡的主要原因。终末期肾病相关性肾细胞癌的病理学类型包括常见的肾细胞癌组织学亚型和独特的组织学亚型,如获得性囊性肾病相关性肾细胞癌和透明细胞乳头状肾细胞癌等,且诊治较为棘手。本文就终末期肾病相关性肾细胞癌的病因、发病率、发病机制、病理分型及预后进行简要综述,有助于提高对终末期肾病相关性肾细胞癌在泌尿系统疾病中的认识。

The increase of the morbidity and mortality of end-stage renal disease is the focus of chronic disease prevention and treatment in China.Renal cell carcinoma associated with end-stage renal disease is the leading cause of death in patients with end-stage renal disease.The pathological types of end-stage renal disease associated renal cell carcinoma include conventional renal cell carcinoma histological subtypes and unique histological subtypes,such as acquired cystic kidney disease associated renal cell carcinoma and clear cell papillary renal cell carcinoma,which are difficult to diagnose and treat.This article reviews the etiology,incidence,pathogenesis,pathological classification,and prognosis of end-stage renal disease associated renal cell carcinoma,which is helpful to improve the understanding of end-stage renal disease associated renal cell carcinoma in urinary diseases.