口腔种植体整合效果的影响因素分析

Analysis of influencing factors on the integration effect of oral implant

目的分析影响口腔种植体整合效果的相关因素。方法回顾性分析苏州大学附属第二医院2019年1月至2020年1月收治的130例口腔种植修复术治疗患者的临床资料。分析术后种植体整合效果,统计年龄、性别、炎症因子水平及牙周指数等一般资料,采用多因素logistic回归分析法分析影响口腔种植修复术后种植体整合效果的独立危险因素。结果130例口腔种植修复术后患者根据整合效果分为良好组(77例)、不良组(53例)。不良组年龄、口腔卫生、种植体斜向植入、垂直骨面型所占比例,白细胞介素(IL)-1、IL-6、IL-8、C-反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α)水平及出血指数(PLI)、菌斑指数(SBI)、探诊深度(PD)高于良好组,差异有统计学意义(P<0.05)。多因素logistic回归分析显示,年龄、口腔卫生、IL-1、IL-6、IL-8、CRP、TNF-α、SBI、PLI、PD、植入方向、垂直骨面型是影响口腔种植修复术后种植体整合效果的独立危险因素(OR>1,P<0.05)。结论口腔种植修复患者术后种植体整合效果除与年龄、口腔卫生状态、植入方向、垂直骨面型有关外,还与炎症因子、牙周指数相关。

Objective To analyze the relevant factors affecting the integration effect of oral implants.Methods The clinical data of 130 patients treated with dental implant repair who were admitted to the Second Affiliated Hospital of Soochow University from January 2019 to January 2020 were retrospectively analyzed.The postoperative implant integration effect was analyzed,and general data such as age,gender,inflammatory factor level and periodontal index were counted,and multivariate logistic regression analysis was used to analyze the independent risk factors affecting the implant integration effect after oral implant restoration.Results A total of 130 patients after oral implant repair were divided into good group(77 cases)and poor group(53 cases)according to the integration effect.Age,oral hygiene,oblique implant placement,proportion of vertical bone profile,interleukin(IL)-1,IL-6,IL-8,C-reactive protein(CRP),and the levels of tumor necrosis factor-α(TNF-α),plaque index(PLI),sulcus bleeding index(SBI),and probing depth(PD)in poor group were higher than those in the good group,and the differences were statistically significant(P<0.05).Multivariate logistic regression analysis showed that age,oral hygiene,IL-1,IL-6,IL-8,CRP,TNF-α,SBI,PLI,PD,implantation direction,and vertical bone profile were risk factors for implant integration after dental implant restoration(OR>1,P<0.05).Conclusion In addition to age,oral hygiene status,implantation direction,and vertical bone profile,the postoperative implant integration effect of patients with oral implant restoration is also related to inflammatory factors and periodontal index.