血清总IgE和过敏原特异性IgE检测在5岁以下儿童哮喘临床诊断中的价值

The value of serum total IgE and allergen-specific IgE detection in the clinical diagnosis of asthma in children under five years old

目的探讨血清总IgE和过敏原特异性IgE检测在5岁以下儿童哮喘临床诊断中的价值。方法选取2019年9月至2020年2月安徽省阜阳市人民医院(以下简称“我院”)住院的30例5岁以下哮喘儿童为哮喘组,另选取我院同期住院的30例5岁以下非过敏体质有咳嗽和/或喘息症状的非哮喘儿童为非哮喘组。比较两组患儿血清总IgE和过敏原特异性IgE抗体的阳性率,分析其在5岁以下儿童哮喘中的诊断价值。结果哮喘组血清总IgE和过敏原特异性IgE抗体阳性率高于非哮喘组(P<0.05)。血清总IgE和过敏原特异性IgE在5岁以下儿童诊断哮喘中的曲线下面积分别是0.800、0.817。结论血清总IgE和过敏原特异性IgE检测在5岁以下儿童哮喘的临床诊断中有较高的价值。

Objective To explore the value of serum total IgE and allergen-specific IgE in the clinical diagnosis of asthma in children under five years old.Methods Thirty asthmatic children under five years old who were hospitalized in Fuyang People’s Hospital of Anhui Province(hereinafter referred to as“our hospital”)from September 2019 to February 2020 were selected as the asthma group,and 30 non-asthmatic children under five years old with cough and/or wheezing symptoms during the same period in our hospital were selected as the non-asthma group.The positive rates of serum total IgE and allergen-specific IgE antibodies were compared between the two groups,and their diagnostic value in asthma in children under five years old was analyzed.Results The positive rate of serum total IgE and allergen-specific IgE antibodies in the asthmatic group was higher than that in the non-asthmatic group(P<0.05).The area under the curve of total serum IgE and allergen-specific IgE were 0.800 and 0.817 respectively.Conclusion The detection of serum total IgE and allergen-specific IgE has a higher response value in the clinical diagnosis of asthma in children under five years old.