终末期肾病血液透析患者并发高血压的影响因素

Influencing factors of hypertension in hemodialysis patients with end-stage renal disease

目的 分析终末期肾病血液透析患者并发高血压的影响因素。方法 采用回顾性分析方法,收集安徽省亳州市人民医院2020年1月至2021年1月收治的100例行血液透析的终末期肾病患者临床资料,根据透析期间患者高血压发生情况将其分为发生组、未发生组。统计两组临床资料,分析终末期肾病血液透析患者并发高血压的影响因素。结果 纳入的100例终末期肾病患者,血液透析期间并发高血压76例,占76.00%。发生组使用促红细胞生成素(EPO)患者占比多于未发生组,血清C反应蛋白(CRP)、同型半胱氨酸(Hcy)、磷(P)水平高于未发生组,差异有统计学意义(P <0.05)。logistic回归结果显示,EPO使用、CRP、Hcy、P产生过多是终末期肾病血液透析患者并发高血压的危险因素(OR> 1,P <0.05)。结论 终末期肾病血液透析患者高血压发生风险较高,EPO使用、血清CRP、Hcy、P产生过多是终末期肾病血液透析患者并发高血压的影响因素。

Objective To analyze the influencing factors of hypertension in hemodialysis patients with end-stage renal disease. Methods A retrospective analysis method was used to collect the clinical data of 100 patients with end-stage renal disease who underwent hemodialysis in the People’s Hospital of Bozhou from January 2020 to January 2021. According to the incidence of hypertension during dialysis, the patients were divided into the occurrence group and the non-occurrence group. The clinical data of the two groups were collected, and the influencing factors of hypertension complicated by end-stage renal disease hemodialysis patients were analyzed. Results Among the 100 patients with end-stage renal disease, a total of 76 cases were complicated with hypertension during hemodialysis, accounting for76.00%. The proportion of patients using erythropoietin(EPO) in the occurrence group was higher than that in the nonoccurrence group, while the levels of serum C-reactive protein(CRP), homocysteine(Hcy), and phosphorus(P) were higher than those in the non occurrence group, and the differences were statistically significant(P < 0.05). Logistic regression analysis showed that, the use of EPO and the excessive production of CRP, Hcy, and P were the risk factors of hypertension in hemodialysis patients with end-stage renal disease(OR > 1, P < 0.05). Conclusion Hemodialysis patients with end-stage renal disease have a higher risk of hypertension, the use of EPO, excessive production of serum CRP, Hcy, and P are the influencing factors of hypertension in hemodialysis patients with end-stage renal disease.