磁共振引导下聚焦超声治疗骨转移瘤的研究进展

Research Progress of MRgFUS in the Treatment of Bone Metastases

骨转移是癌症三大常见的转移部位之一,疼痛和骨破坏是其最常见的症状,严重影响人们的生活质量。磁共振引导下聚焦超声(MRgFUS)作为一种非侵入性、无电离辐射、无剂量限制、可以重复治疗的治疗方式,在癌性疼痛缓解和肿瘤进展控制方面取得了显著的临床疗效。本文从MRgFUS治疗骨转移瘤的基本原理、手术方法、治疗标准、疗效评价、治疗并发症及预防等方面,对MRgFUS治疗骨转移瘤的相关研究进行综合分析,以期为后期的临床应用提供参考。

Bone metastasis is one of the three common metastatic sites of cancer.Pain and bone destruction are the most common symptoms,which seriously affect people′s quality of life.Magnetic resonance-guided focused ultrasound(MRgFUS),as a non-invasive,non-ionizing radiation,non-dose limiting and repeatable treatment modality,has achieved significant clinical efficacy in cancer pain relief and tumor progression control.In this article,the basic principles,surgical methods,treatment standards,efficacy evaluation,treatment complications and prevention of MRgFUS in the treatment of bone metastases are comprehensively analyzed,so as to provide reference for the later clinical application.