t检验和HorRat方程在方法验证中的应用

Application of t Test and HorRat Equation in Method Verification

根据CNAS CL01-2018《检测和校准实验室能力认可准则》和RB/T 214—2017《检验检测机构资质认定能力评价检验检测机构通用要求》,方法验证是实验室引入新方法时必做的工作。然而,部分实验缺乏相应的标准物质,不能直接反应检测结果的正确度和精密度等信息。采用t检验和Hor Rat方程对检测项目的方法验证进行分析。对两组实验结果,采用t检验分析方法的正确性,通过Hor Rat方程分析方法的精密度,验证实验室的检测能力是否满足方法标准的要求。

According to the requirements of CNAS CL01-2018"Accreditation criteria for the competency of testing and calibration laboratories"and RB/T 214-2017"Competence assessment for inspection body and laboratory mandatory approval-General requirements for inspection body and laboratory",method validation is a necessary work for the laboratory to introduce new methods.However,some experiments lack corresponding reference materials and cannot directly reflect the accuracy and precision of the test results.In this paper,t-test and HorRat equation are used to analyze the method verification of test items.For two groups of experimental results,t-test analysis method was used for correctness,and HorRat equation analysis method was used for accuracy,so as to verify the laboratory's testing ability.