红细胞单采术治疗煤矿地区继发性红细胞增多症临床观察

Clinical observation on the treatment of secondary erythrocytosis in coal mine area by therapeutic hemapheresis

目的:观察红细胞单采术治疗继发性红细胞增多症患者的临床效果。方法:选取2019年9月—2020年9月接诊的继发性红细胞增多症患者130例,使用血细胞分离机进行红细胞单采术治疗,观察治疗前后患者的血细胞比容、血红蛋白、白细胞、血小板变化;观察治疗后血红蛋白再次大于180 g/L的时间,预测需再次单采的间隔时间。结果:患者治疗前后血红蛋白、血细胞比容明显下降(P<0.05),明显改善了患者头晕、头痛、耳鸣等红细胞增多症状。白细胞、血小板治疗前后比较,差异无统计学意义(P>0.05)。血红蛋白再次大于180 g/L的时间间隔为(192.45±54.84)d。结论:红细胞单采术适用于继发性红细胞增多症的患者。

Objective:To observe the clinical effect of therapeutic hemapheresis in the treatment of secondary erythrocytosis.Methods:A total of 130 patients with secondary polycythemia who were admitted from September 2019 to September 2020 were selected,and a blood cell separator was used for hematopoietic treatment,and the changes of hematocrit,hemoglobin,white blood cells,and platelets of the patients before and after treatment were observed.To observe the time when the hemoglobin is greater than 180 g/L again after treatment,and predict the interval time for re-apheresis.Results:Hemoglobin and hematocrit decreased significantly before and after treatment(P<0.05),and the symptoms of hypererythrocyte such as dizziness,headache and tinnitus were significantly improved.There were no significant changes in WBC and platelet before and after treatment(P>0.05).The interval between hemoglobin>180 g/L again was(192.45±54.84)day.Conclution:Therapeutic erythroapheresis is suitable for patients with secondary erythrocytosis and has good clinical application value.