依托咪酯或丙泊酚复合咪哒唑仑及芬太尼麻醉 在老年无痛结肠镜检查治疗中的比较

Comparison of Etomidate or Propofol Combined with Midazolam and Fentanyl Anesthesia in Treatment of Elderly Painless Colonoscopy

目的:比较依托咪酯与丙泊酚复合咪哒唑仑及芬太尼麻醉在老年患者无痛结肠镜检查治疗中应用效果。方法:选取2020年1-12月在山东国欣颐养集团淄博医院行无痛结肠镜检查治疗的老年患者180例,随机分为两组,各90例。依托咪酯组静脉注射咪达唑仑、芬太尼、依托咪酯,丙泊酚组静脉注射咪达唑仑、芬太尼、丙泊酚。比较两组患者苏醒时间、不良反应发生率、心率及血压下降等情况。结果:两组麻醉苏醒时间比较,差异无统计学意义(P>0.05)。依托咪酯组心率、血压下降程度均明显低于丙泊酚组,差异有统计学意义(P<0.05)。丙泊酚组不良反应发生率明显高于依托咪酯组,差异有统计学意义(P<0.05)。结论:依托咪酯复合咪达唑仑及芬太尼麻醉在老年患者无痛结肠镜检查治疗中具有良好的应用效果,麻醉后的生命体征更为稳定,对患者身体影响更小,更适宜老年患者使用。

Objective:To compare the application effect of etomidate and propofol combined with midazolam and fentanyl anesthesia in the treatment of painless colonoscopy in elderly patients.Methods:From January to December in 2020,180 elderly patients who underwent painless colonoscopy in Zibo Hospital of Shandong Guoxin Healthcare Group were selected,and they were randomly divided into the two groups with 90 cases in each group.The etomidate group received intravenous injection of midazolam,fentanyl,and etomidate.The propofol group received intravenous injection of midazolam,fentanyl,and propofol.The patient's recovery time,incidence of adverse reactions,decrease in heart rate and blood pressure were compared between the two groups.Results:There was no statistically significant difference in the recovery time from anesthesia between the two groups(P>0.05).The decrease in heart rate and blood pressure in the etomidate group was significantly lower than that in the propofol group,the difference was statistically significant(P<0.05).The incidence of adverse reactions in the propofol group was significantly higher than that in the etomidate group,the difference was statistically significant(P<0.05).Conclusion:Etomidate combined with midazolam and fentanyl anesthesia has a good application effect in the treatment of painless colonoscopy in elderly patients.The vital signs after anesthesia are more stable,and the patient's body is scarcely influenced,which is more suitable for elderly patients.