以口腔溃疡为首发症状的鼻型-结外自然杀伤/T细胞淋巴瘤1例

Nasal-type extranodal natural killer/T-cell lymphoma with oral ulcer as the earliest clinical manifestation

鼻型-结外自然杀伤/T细胞淋巴瘤(ENKTL-NT)是源于自然杀伤细胞或者细胞毒性T细胞的非霍奇金淋巴瘤的一个特殊亚型,以口腔溃疡为首发症状的情况因罕见和认识不足使其诊断具有挑战性。本文报道1例以口腔溃疡为首发症状的ENKTL-NT,并通过分析该疾病的临床病理学特征、鉴别诊断、治疗及预后、误诊原因,为临床诊治提供参考。

Nasal-type extranodal natural killer/T-cell lymphoma(ENKTL-NT)is a special subtype of non-Hodgkin’s lymphoma derived from natural killer cells or cytotoxic T cells.Oral ulcers as the first symptom makes its diagnosis challenging because of its rarity and lack of understanding.We report a case of ENKTL-NT in this paper.We analyzed the clinicopathological features,differential diagnosis,treatment,prognosis and the causes of misdiagnosis to provide a diagnostic basis for dentists to make better clinical diagnosis and treatment.