化痰通络方联合醒脑开窍针法治疗脑梗死后遗症患者的效果

Effects of Huatan Tongluo recipe combined with Xingnao Kaiqiao acupuncture in treatment of patients with sequelae of cerebral infarction

目的:观察化痰通络方联合醒脑开窍针法治疗脑梗死后遗症患者的效果。方法:选取100例脑梗死后遗症患者为研究对象,采用随机数字表法分为对照组和观察组各50例。两组均予以硫酸氢氯吡格雷、阿司匹林治疗,在此基础上,对照组给予醒脑开窍针法治疗,观察组在对照组基础上联合化痰通络方治疗,比较两组临床疗效、治疗前后中医证候积分、神经功能缺损[美国国立卫生研究院卒中量表(NIHSS)]评分、肢体运动功能[Fugl-Meyer运动功能表(FMA)]评分、颅内动脉平均血流速度(Vm)和不良反应发生率。结果:观察组治疗总有效率为96.00%(48/50),高于对照组的80.00%(40/50),差异有统计学意义(P<0.05);治疗后,观察组半身不遂、口舌歪斜、头晕目眩等中医证候积分均低于对照组,差异有统计学意义(P<0.05);观察组NIHSS评分低于对照组,FMA评分高于对照组,差异有统计学意义(P<0.05);观察组大脑前、中、后动脉Vm均高于对照组,差异有统计学意义(P<0.05);两组治疗期间未见明显不良反应。结论:化痰通络方联合醒脑开窍针法治疗脑梗死后遗症患者可提高治疗总有效率、FMA评分和Vm,降低中医证候积分和NIHSS评分,效果优于单纯醒脑开窍针法治疗。

Objective:To observe effects of Huatan Tongluo recipe combined with Xingnao Kaiqiao acupuncture in treatment of patients with sequelae of cerebral infarction.Methods:100 patients with sequelae of cerebral infarction were selected as the research objects,and were divided into control group and observation group by using the random number table method,50 cases in each group.Both groups were treated with Clopidogrel hydrogen sulfate and Aspirin.On this basis,the control group was treated with Xingnao Kaiqiao acupuncture,while the observation group was treated with Huatan Tongluo recipe on the basis of that of the control group.The clinical effects,the TCM syndrome score,the neurological deficit[National Institutes of Health Stroke Scale(NIHSS)]score,the limb motor function[Fugl-Meyer motor function assessment(FMA)]score,the intracranial artery mean blood flow velocity(Vm)and the incidence of adverse reactions were compared between the two groups before and after the treatment.Results:The total effective rate of the observation group was 96.00%(48/50),which was higher than 80.00%(40/50)of the control group,and the difference was statistically significant(P<0.05).After the treatment,the scores of TCM syndromes such as hemiplegia,skewed tongue and dizziness in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).The NIHSS score of the observation group was lower than that of the control group,the FMA score was higher than that of the control group,and the differences were statistically significant(P<0.05).The Vm levels of the anterior,middle and posterior cerebral arteries in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).However,there were no obvious adverse reactions in the two groups during the treatment.Conclusions:Huatan Tongluo recipe combined with Xingnao Kaiqiao acupuncture in the treatment of the patients with sequelae of cerebral infarction can improve the total effective rate,the FMA score and the Vm,and reduce the TCM syndrome score and the NIHSS score.Moreover,it is superior to single Xingnao Kaiqiao acupuncture.