庞国明教授经验方治疗2型糖尿病患者的临床疗效观察

Clinical Observation of Professor Pang Guoming’s Experience Prescription in the Treatment of Patients with Type 2 Diabetes Mellitus

目的:分析庞国明教授经验方治疗2型糖尿病患者的临床效果。方法:选择2019年1月—2020年1月开封市中医院收治的83例2型糖尿病胃轻瘫患者。使用随机数表法将患者分成对照组41例和观察组42例。对照组患者口服二甲双胍,观察组患者使用庞国明教授经验方治疗。比较两组患者血脂水平、血糖水平、中医症候积分、不良反应。结果:两组患者总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)水平在治疗前相同,差异无统计学意义(t=74.648、19.782、21.874、13.625,P>0.05),干预后观察组患者TC、TG、HDL-C、LDL-C水平低于对照组,差异有统计学意义(t=31.337、23.957、11.574、23.669,P<0.05)。治疗前两组患者空腹血糖(FPG)、餐后24 h血糖(24 hPG)水平比较,差异无统计学意义(t=9.97、11.504,P>0.05),干预后观察组患者FPG、24 hPG水平低于对照组,差异有统计学意义(t=13.227、13.874,P<0.05)。治疗前两组患者早饱、胃脘胀、纳差、舌像和脉像评分比较,差异无统计学意义(P>0.05),治疗后观察组患者早饱、胃脘胀、纳差、舌像和脉像评分低于对照组,差异有统计学意义(t=20.614、26.112、36.015、14.748,P<0.05)。观察组患者不良反应率低于对照组,差异有统计学意义(χ^(2)=6.193,P<0.05)。结论:庞国明教授经验方治疗2型糖尿病胃轻瘫疗效确切,建议推广。

Objective: To investigate the clinical efficacy of the experience of professor PANG Guo-ming in treating type 2 diabetes mellitus. Methods: A total of 83 patients with type 2 diabetic gastroparesis who were diagnosed and treated in the hospital from January 2019 to January 2020 were selected and divided into a control group of 41 cases and an observation group of 42 cases using the random number table method. The patients in the control group were treated with oral metformin, and the patients in the observation group were treated with Professor Pang Guoming’s experience prescription. The blood lipid levels, blood sugar levels,TCM symptom scores and adverse reactions were compared between the two groups. Results: The levels of TC, TG, HDL-C and LDL-C in the two groups were the same before treatment, and the difference was not statistically significant(t=74.648, 19.782,21.874, 13.625, P>0.05). After intervention, the levels of TC, TG, HDL-C and LDL-C in the observation group were lower than those in the control group, and the difference was statistically significant(t=31.337, 23.957, 11.574, 23.669, P<0.05). There was no statistically significant difference in the levels of FPG and 24 hPG between the two groups before treatment(t=9.970, 11.504,P>0.05). After intervention, the levels of FPG and 24 hPG in the observation group were lower than those in the control group,and the difference was statistically significant(t=13.227, 13.874, P<0.05). There was no statistically significant difference in the scores of early satiety, epigastric distention, anorexia, tongue image and pulse image between the two groups before treatment(P>0.05). After treatment, the scores of early satiety, epigastric distention, anorexia, tongue image and pulse image in the observation group were lower than those in the control group, and the difference was statistically significant(t=20.614, 26.112, 36.015, 16.247,14.748, P<0.05). The adverse reaction rate in the observation group was lower than that in the control group, and the difference was statistically significant(χ^(2)=6.193, P<0.05). Conclusion: Professor Pang Guoming’s experience formula is effective in treating type 2 diabetic gastroparesis, and it is recommended to be promoted.