类固醇激素在甲状腺手术中保护喉返神经功能的效果及对恢复时间的影响

Effect of steroid hormone on the protection of recurrent laryngeal nerve function and recovery time in thyroid surgery

目的探讨研究类固醇激素在甲状腺手术中保护喉返神经功能的效果及对恢复时间的影响。方法回顾性分析2019年9月至2020年9月于江西省景德镇市第三人民医院行甲状腺手术治疗的60例患者的临床资料,根据治疗方法的差异性分为观察组(n=30)和对照组(n=30)。其中,对照组仅予以手术治疗,不予以其他特殊处理,观察组选择手术期间配合类固醇激素进行治疗,比较两组患者的临床效果及喉返神经功能恢复时间。结果观察组声音嘶哑、喉返神经损伤发生率分别为63.33%、10.00%,与对照组(66.67%、16.66%)比较,差异无统计学意义(χ^(2)=0.07、0.57,P>0.05);观察组的喉返神经功能恢复时间短于对照组,PSQI评分高于对照组,差异有统计学意义(t=6.88、12.65,P<0.05)。结论患者行甲状腺手术期间,采用类固醇激素来保护其喉返神经功能,能有效加快患者功能恢复时间,避免喉返神经损伤,提高其睡眠质量,预后效果显著,值得临床大力推广。

Objective To investigate the effect of steroid hormone on protecting recurrent laryngeal nerve function and recovery time in thyroid surgery.Methods The clinical data of 60 patients who underwent thyroid surgery in the Third People's Hospital of Jingdezhen in Jiangxi Province from September 2019 to September 2020 were retrospectively analyzed.The patients were divided into the observation group and the control group according to the differences in treatment methods.The control group was only treated with surgery without special treatment,and the observation group was treated with steroid hormone during surgery.The clinical effect and recovery time of recurrent laryngeal nerve function were compared between the two groups.Results The incidence rate of hoarseness and recurrent laryngeal nerve injury in the observation group was 63.33% and 10.00%,respectively,which was not significantly different from the corresponding values of 66.67% and 16.66% in the control group(χ^(2)=0.07,0.57,P>0.05).The recovery time of recurrent laryngeal nerve function in the observation group was higher than that in the control group,and the PSQI score of the observation group was higher than the control group.The difference had statistical significance(t=6.88,12.65,P<0.05).Conclusion During thyroid surgery,the use of steroid hormone to protect the recurrent laryngeal nerve function can effectively accelerate the functional recovery time of patients,avoid damage to the recurrent laryngeal nerve,and improve their sleep quality.It has a significant effect and is worthy of clinical promotion.