高脂血症、高血压、脑卒中及骨质疏松症是良性阵发性位置性眩晕复发的危险因素

Hyperlipidemia,hypertension,stroke,and osteoporosis are risk factors for relapse of benign paroxysmal positional vertigo

目的探讨分析良性阵发性位置性眩晕复发的影响因素,为临床防治该疾病提供依据。方法采用随机抽样法抽取2019年1月至2020年1月浙江省台州医院收治的良性阵发性位置性眩晕患者150例,通过调查表收集相关数据资料,对本研究纳入患者进行为期1年的随访,根据随访结果有无复发良性阵发性位置性眩晕将研究对象分为复发组与无复发组,进行单因素分析及进一步的多因素分析。结果良性阵发性位置性眩晕患者的复发率为21.92%(32/146)。复发组患者伴高脂血症、高血压、脑卒中及骨质疏松症的比例明显高于无复发组患者,差异有统计学意义(P<0.05)。多因素logistic分析结果显示,高脂血症(OR=4.985,P=0.023)、高血压(OR=3.866,P=0.035)、脑卒中(OR=9.750,P=0.011)以及骨质疏松症(OR=8.159,P=0.016)为良性阵发性位置性眩晕复发的独立危险因素。结论高脂血症,高血压,脑卒中及骨质疏松症为良性阵发性位置性眩晕复发的独立危险因素,应对伴上述危险因素的患者采取相应的措施,降低良性阵发性位置性眩晕的复发率。

Objective To explore and analyze the factors affecting the relapse of benign paroxysmal positional vertigo(BPPV),so as to provide a basis for clinical prevention and treatment of this disease.Methods A total of 150 patients with BPPV admitted to Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University from January 2019 to January 2020 were randomly selected as observation subjects,and relevant data were collected by using questionnaires.The patients included in this study were followed up for one year,and they were divided into the relapse group and the non-relapse group based on the presence or absence of BPPV relapses during the follow-up.Univariate analysis and further multivariate analysis were conducted on both groups.Results The relapse rate of patients with BPPV was 21.92%(32/146).The proportion of patients with hyperlipidemia,hypertension,stroke and osteoporosis in the relapse group was significantly higher than that in the non-relapse group,with statistically significant differences(P<0.05).Multivariate logistic analysis showed that hyperlipidemia(OR=4.985,P=0.023),hypertension(OR=3.866,P=0.035),stroke(OR=9.750,P=0.011)and osteoporosis(OR=8.159,P=0.016)were independent risk factors for relapse of BPPV.Conclusion Hyperlipidemia,hypertension,stroke and osteoporosis are independent risk factors for relapse of BPPV,and countermeasures should be taken to reduce the relapse rate of BPPV in patients with these risk factors.