在第一产程应用间苯三酚对产妇产程持续时间、宫颈水肿及新生儿结局的影响

Effects of phloroglucinol in the first stage of labor on duration of labo r,cervical edema,and neonatal outcomes

目的:探讨在第一产程为产妇应用间苯三酚对其产程持续时间、宫颈水肿情况及新生儿结局的影响。方法:选取2019年5月至2020年9月在高州市妇幼保健院进行分娩的产妇120例为研究对象。采用抽签法将其分为对照组和观察组,每组60例产妇。在第一产程,为对照组产妇应用缩宫素,在此基础上为观察组产妇应用间苯三酚。然后对比两组产妇宫颈水肿治疗的总有效率、产程持续的时间、疼痛情况及新生儿不良结局的发生率。结果:1)观察组产妇宫颈水肿治疗的总有效率(98.33%)高于对照组产妇宫颈水肿治疗的总有效率(81.67%),P<0.05。2)观察组产妇新生儿不良结局的发生率(1.67%)低于对照组产妇新生儿不良结局的发生率(8.33%),P<0.05。3)观察组产妇第一产程潜伏期持续的时间、第一产程活跃期持续的时间、第二产程持续的时间、第三产程持续的时间均短于对照组产妇,其宫口扩张的速度高于对照组产妇,P<0.05。4)在第一产程期间、产后,观察组产妇的VAS评分均低于对照组产妇,P<0.05。结论:在第一产程为产妇应用间苯三酚可缩短其产程持续的时间,缓解其疼痛症状,改善其宫颈水肿情况,降低其新生儿不良妊娠结局的发生率。

Objective:To investigate the effects of phloroglucinol on the duration of labor,cervical edema and neonatal outcome in the first stage of labor.Methods:A total of 120 parturitions who delivered in Gaozhou Maternal and Child Health Care Hospital from May 2019 to September 2020 were selected as the research object.They were divided into control group and observation group by drawing lots,with 60 parturients in each group.During the first stage of labor,the control group was given oxytocin,and the observation group was given phloroglucinol.Then,the total effective rate,duration of labor,pain and incidence of neonatal adverse outcomes were compared between the two groups.Results:1)The total effective rate of cervical edema treatment in the observation group(98.33%)was higher than that in the control group(81.67%),P<0.05.2)The incidence of adverse maternal and newborn outcomes in the observation group(1.67%)was lower than that in the control group(8.33%),P<0.05.3)The duration of the latency period of the first labor stage,the duration of the active period of the first labor stage,the duration of the second labor stage and the duration of the third labor stage in the observation group were shorter than those in the control group,and the speed of uterine orificium dilation was higher than that in the control group,P<0.05.4)VAS score in the observation group was lower than that in the control group during the first labor and postpartum period,P<0.05.Conclusion:Phloroglucinol in the first stage of labor can shorten the duration of labor,relieve pain symptoms,improve cervical edema,and reduce the incidence of adverse neonatal pregnancy outcomes.