综合性护理联合特殊护理在奥美拉唑治疗反流性食管炎患者中的应用效果

Application Effect of Comprehensive Nursing Combined with Special Nursing in Omeprazole Treatment of Reflux Esophagitis

目的分析综合性护理联合特殊护理在奥美拉唑治疗反流性食管炎患者中的应用效果。方法回顾分析我院2018年4月至2020年2月收治的60例反流性食管炎患者,按护理方式的不同进行分组,其中30例接受常规护理(对照组),另30例接受综合性护理联合特殊护理(观察组),比较两组的护理效果,包括胃泌素、胃动素、治疗依从性等。结果观察组治疗依从性评分为(8.64±0.65)分,高于对照组的(5.68±0.24)分,差异有统计学意义(P<0.05);护理前,两组胃动素(t=0.0036)、胃泌素(t=0.0055)、血管活性肽(t=0.1269)比较,差异无统计学意义(P>0.05);护理后,观察组胃动素(t=5.4292)高于对照组,胃泌素(t=14.6274)、血管活性肽(t=51.9989)低于对照组,差异有统计学意义(P<0.05);护理前,两组患者肿瘤坏死因子-α(t=0.0944)、白细胞介素-8(t=0.0294)、白细胞介素-6(t=0.1881)比较,差异无统计学意义(P>0.05);护理后,观察组肿瘤坏死因子-α(t=16.1220)、白细胞介素-8(t=19.1619)、白细胞介素-6(t=15.6774)低于对照组,差异无统计学意义(P<0.05);护理前,两组患者症状积分(t_(反酸嗳气)=0.1758、t_(烧心)=1.2310、t_(胸骨后疼痛)=0.1758、t_(胃脘疼痛)=1.7320、t_(反酸嗳气)=0.7035)比较,差异无统计学意义(P>0.05);护理后,观察组症状积分低于对照组(t_(反酸嗳气)=39.6198、t_(烧心)=25.9729、t_(胸骨后疼痛)=81.4063、t_(胃脘疼痛)=59.6439、t_(反酸嗳气)=21.8102),差异无统计学意义(P<0.05);护理前,两组患者SF-36评分比较(t_(情感活动)=0.2388、t_(精神状态)=1.1270、t_(活力)=0.5884、t_(生理功能)=1.1147、t_(躯体疼痛)=0.2437、t_(社会功能)=0.0927),差异无统计学意义(P>0.05);护理后,观察组SF-36评分高于对照组(t_(情感活动)=20.6157、t_(精神状态)=21.2770、t_(活力)=23.0666、t_(生理功能)=35.1560、t_(躯体疼痛)=31.9064、t_(社会功能)=20.9515),差异无统计学意义(P<0.05)。结论反流性食管炎患者在接受奥美拉唑治疗期间,给予综合护理联合特殊护理,可使患者的胃泌素、胃动素均得到明显改善,且治疗依从性较高。

Objective To analyze the application effect of comprehensive nursing combined with special nursing in omeprazole treatment of reflux esophagitis.Methods A total of 60 cases of patients with reflux esophagitis and who treated in our hospital from April 2018 to February 2020 were retrospectively analyzed,and the patients were grouped according to the nursing methods,30 cases received routine nursing(control group)and other 30 cases received comprehensive nursing combined with special nursing(observation group).The nursing effect were compared,such as gastrin,motilin,treatment compliance,etc.Results The treatment compliance score of the observation group was(8.64±0.65)points,which was higher than that of the control group(5.68±0.24)points,and the difference was statistically significant(P<0.05).Before nursing,there was no significant difference in motilin(t=0.0036),gastrin(t=0.0055)and vasoactive peptide(t=0.1269)between the two groups(P>0.05).After nursing,motilin(t=5.4292)in the observation group was higher than that in the control group,gastrin(t=14.6274)and vasoactive peptide(t=51.9989)were lower than those in the control group,the difference was statistically significant(P<0.05).Before nursing,tumor necrosis factor-α(t=0.0944),interleukin-8(t=0.0294)and interleukin-6(t=0.1881),there was no significant difference(P>0.05).After nursing,tumor necrosis factor in the observation group-α(t=16.1220),interleukin-8(t=19.1619)and interleukin-6(t=15.6774)were lower than those in the control group,and the difference was not statistically significant(P<0.05).Before nursing,there was no significant difference in symptom scores between the two groups(tacid reflux belching=0.1758,theartburn=1.2310,tsternal pain=0.1758,tepigastric pain=1.7320,tacid reflux belching=0.7035)(P>0.05);After nursing,the symptom score of the observation group was lower than that of the control group(tacid reflux belching=39.6198,theartburn=25.9729,tsternal pain=81.4063,tepigastric pain=59.6439,tacid reflux belching=21.8102),and the difference was not statistically significant(P<0.05);Before nursing,there was no significant difference in SF-36 scores between the two groups(temotional activity=0.2388,tmental state=1.1270,tvitality=0.5884,tphysiological function=1.1147,tphysical pain=0.2437,tsocial function=0.0927)(P>0.05).After nursing,the SF-36 score of the observation group was higher than that of the control group(temotional activity=20.6157,tmental state=21.2770,tvitality=23.0666,tphysiological function=35.1560,tphysical pain=31.9064,tsocial function=20.9515),and the difference was not statistically significant (P<0.05). Conclusion During the treatment of omeprazole, patients with reflux esophagitis were given comprehensive nursing combined with special nursing, which the gastrin and motilin are significantly improved, and the treatment compliance is high.