彩色多普勒超声在甲状腺结节良恶性鉴别诊断中的应用价值分析

Analysis of the application value of color Doppler ultrasonography in differential diagnosis of benign and malignant thyroid nodules

目的探究彩色多普勒超声在甲状腺结节良恶性鉴别诊断中的应用价值。方法130例甲状腺结节患者,均采用彩色多普勒超声检查。以手术病理结果作为金标准,分析彩色多普勒超声诊断符合率;对比良性结节和恶性结节的钙化情况、血流信号分级;观察良性结节和恶性结节的彩色多普勒超声影像学特征。结果将手术病理结果作为金标准,130例患者中良性结节97例,恶性结节33例。彩色多普勒超声诊断结果与手术病理结果符合125例,其中恶性结节29例,良性结节96例,诊断符合率为96.15%(125/130)。恶性结节钙化率为78.79%,明显高于良性结节的17.53%,差异具有统计学意义(P<0.05)。恶性结节血流信号主要为Ⅱ级、Ⅲ级,良性结节血流信号主要为Ⅰ级。良性结节和恶性结节的血流信号分级对比差异具有统计学意义(P<0.05)。彩色多普勒超声检查显示:良性结节内部回声均匀,主要是等回声、低回声、高回声,后方回声无衰减,边界清晰,包膜完整,形状规则,周边声晕规整;恶性结节内部回声主要是极低回声或无回声,回声不均匀,后方回声衰减,边界不清晰,包膜不完整,形状不规则,无周边声晕。结论彩色多普勒超声对甲状腺结节的诊断符合率高,能够有效鉴别良性和恶性结节,可以清晰显示结节的影像学特征等,具有重要的临床推广价值。

Objective To investigate the application value of color Doppler ultrasonography in differential diagnosis of benign and malignant thyroid nodules.Methods 130 patients with thyroid nodules were examined by color Doppler ultrasonography.Using the surgical pathology results as the gold standard,the diagnostic coincidence rate of color Doppler ultrasonography was analyzed.The calcification and blood flow signal grading of benign and malignant nodules were compared,and the color Doppler ultrasonography imaging features of benign and malignant nodules were observed.Results Using the surgical pathology results as the gold standard,there were 97 benign nodules and 33 malignant nodules among 130 patients.The diagnostic results of color Doppler ultrasonography were consistent with the surgical pathology results in 125 cases,including 29 malignant nodules and 96 benign nodules,with a diagnostic compliance rate of 96.15%(125/130).The calcification rate of malignant nodules was 78.79%,which was significantly higher than 17.53%of benign nodules,and the difference was statistically significant(P<0.05).The blood flow signal of malignant nodules was mainly gradeⅡand gradeⅢ,and the blood flow signal of benign nodules was mainly gradeⅠ.The difference in blood flow signal grading between benign and malignant nodules was statistically significant(P<0.05).Color Doppler ultrasonography showed that the internal echo of the benign nodule was uniform,mainly isoechoic,hypoechoic,and hyperechoic,with no attenuation of the posterior echo,clear boundary,intact capsule,regular shape,and regular surrounding halo;the internal echo of malignant nodules were mainly extremely hypoechoic or anechoic,with uneven echo,attenuated posterior echo,unclear boundary,incomplete capsule,irregular shape,and irregular peripheral halo.Conclusion Color Doppler ultrasonography has a high diagnostic rate for thyroid nodules,and can effectively identify benign and malignant nodules,and can clearly show the imaging features of nodules,etc.It has important clinical promotion value.