支气管肺泡灌洗氨溴索治疗急性肺脓肿的临床疗效分析

Analysis of Clinical Efficacy of Bronchoalveolar Lavage with Ambroxol in the Treatment of Acute Lung Abscess

目的研究支气管肺泡灌洗氨溴索治疗急性肺脓肿的临床疗效。方法选取2019年1月—2021年10月该院收治的急性肺脓肿患者86例,根据随机数表法,将患者分为两组,每组43例。对照组采用常规治疗,观察组采用支气管肺泡灌洗氨溴索治疗,观察两组临床治疗效果。结果观察组临床疗效比对照组更高(97.67%vs 79.07%),差异有统计学意义(χ^(2)=7.242,P<0.05);观察组灌洗次数(4.28±1.22)次、抗菌药疗程(60.73±4.25)d以及住院时间(16.17±2.63)d均比对照组更少,差异有统计学意义(t=3.928、23.443、13.843,P<0.05);治疗后,观察组焦虑(SAS)与抑郁(SDS)评分分别为(48.12±4.16)分、(47.29±4.16)分均比对照组更低,差异有统计学意义(t=6.226、7.191,P<0.05);观察组生理功能、躯体功能、社会功能、情感职能、精神健康、总体健康分别为(78.27±8.81)分、(72.91±7.54)分、(82.83±8.33)分、(68.71±7.15)分、(75.19±8.24)分、(85.94±7.38)分均比对照组更高,差异有统计学意义(t=9.777、7.938、6.386、8.329、7.441、9.932,P<0.05)。结论针对急性肺脓肿患者,通过支气管肺泡灌洗氨溴索治疗,能够提高治疗效果,减少患者治疗时间,有效提高生活质量,值得推广。

Objective To study the clinical effect of bronchoalveolar lavage with ambroxol in the treatment of acute lung abscess.Methods A total of 86 patients with acute lung abscess who were admitted to the hospital from January 2019 to October 2021 were selected,according to the random number table method.The patients were divided into two groups,43 cases in each group.The control group received conventional treatment,while the observation group received bronchoalveolar lavage with ambroxol.The clinical treatment effects of the two groups were observed.Results The clinical efficacy of the observation group was higher than that of the control group(97.67%vs 79.07%),the difference was statistically significant(χ^(2)=7.242,P<0.05).The number of lavages(4.28±1.22)times,the course of antibiotics(60.73±4.25)d and the length of hospital stay(16.17±2.63)d in the observation group were all less than those in the control group,the difference was statistically significant(t=3.928,23.443,13.843,P<0.05).After treatment,the anxiety(SAS)and depression(SDS)scores of the observation group were(48.12±4.16)points and(47.29±4.16)points lower than those of the control group,the difference was statistically significant(t=6.226,7.191,P<0.05).Physiological function,physical function,social function,emotional function,mental health,and general health of the observation group were respectively(78.27±8.81)points,(72.91±7.54)points,(82.83±8.33)points,(68.71±7.15)points,(75.19±8.24)points,(85.94±7.38)points,were higher than those in the control group,the difference was statistically significant(t=9.777,7.938,6.386,8.329,7.441,9.932,P<0.05).Conclusion For patients with acute lung abscess,bronchoalveolar lavage with ambroxol can improve the therapeutic effect,reduce the treatment time of patients,and effectively improve the quality of life,which is worthy of promotion.