摘要
支气管哮喘(简称哮喘)和肥胖是困扰儿童健康的两大慢性疾病,目前两类疾病的患病率仍呈上升趋势,且二者之间相互作用,互为因果。该文对儿童肥胖性哮喘的临床特点、特应性、潜在生物标记物,以及肥胖介导的代谢异常和免疫反应,包括脂肪中的炎症因子和脂肪因子在肥胖性哮喘中的作用进行了综述。
Bronchial asthma and obesity are two chronic diseases that do harm to children′s health.The incidence of the two diseases is increasing,and they promote each other appearing to be causal.This paper reviews the clinical characteristics,atopy,potential biomarkers of obese asthma in children,as well as obesity-mediated metabolic abnormalities and immune responses,including inflammatory factors in fat and the role of adipokines in obese asthma.
作者
黄书慧(综述)
刘长山(审校)
Huang Shuhui;Liu Changshan(Department of Pediatrics,The Second Hospital of Tianjin Medical University,Tianjin 300211,China)
出处
《国际儿科学杂志》
2022年第4期258-261,共4页
International Journal of Pediatrics
基金
天津市卫生行业重点攻关项目(16KG116)。
关键词
儿童
哮喘
肥胖
生物标记物
炎症因子
Children
Asthma
Obesity
Biomarkers
Inflammatory factor
