墨玉县成年人群血脂异常调查

Prevalence of dyslipidemia among adults in Moyu County

目的了解新疆维吾尔自治区和田地区墨玉县成年人群血脂异常的流行情况,为预防和控制血脂异常提供依据。方法收集2018—2019年墨玉县≥18岁常住居民健康体检资料,包括人口学信息、身高、体重、血压和血生化指标检测结果等;描述性分析居民血脂异常流行特征。结果调查166142人,年龄为(41.08±15.72)岁;男性77744人,占46.76%;肥胖34728例,占20.90%;糖尿病5776例,占3.48%;高血压26294例,占15.83%。三酰甘油(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)和低密度脂蛋白胆固醇(LDL-C)水平分别为(1.38±0.98)、(4.13±1.19)、(1.31±0.41)和(2.25±0.77)mmol/L。检出血脂异常49373例,检出率为29.72%,其中高TG血症、高TC血症、低HDL-C血症和高LDL-C血症检出率分别为9.73%、4.59%、19.65%和1.99%。男性血脂异常检出率为33.97%,高于女性的25.98%(χ^(2)=1264.729,P<0.001)。随年龄、体质指数增加,血脂异常检出率呈上升趋势(χ^(2)_(趋势)=539.382、3601.833,均P<0.001)。高血压和糖尿病患者血脂异常检出率均较高(χ^(2)=497.251、766.142,均P<0.001),分别为35.48%和46.07%。有2项及以上血脂指标异常9059例,占18.35%;肥胖、高血压、糖尿病患者中有2项及以上血脂指标异常分别占26.50%、24.14%和33.15%。结论墨玉县成年人群血脂异常检出率低于全国水平,以低HDL-C血症最常见。肥胖、高血压和糖尿病患者的血脂异常患病率较高且同时合并多项血脂指标异常。

Objective To investigate the prevalence of dyslipidemia among adults in Moyu County,Hotan Prefecture,Xinjiang Uygur Autonomous Region,so as to provide insights into the management of dyslipidemia.Methods The physical examination data of permanent residents at ages of 18 years and older were collected from Moyu County from 2018 to 2019,including demographic features,height,body weight,blood pressure and blood biochemical parameter mea⁃surements.The epidemiological characteristics of dyslipidemia were analyzed among residents.Results Totally 166142 adults were investigated,with a mean age of(41.08±15.72)years.There were 77744 men(46.76%),34728 obese adults(20.90%),5776 adults with diabetes(3.48%)and 26294 adults with hypertension(15.83%).The levels of tri⁃glyceride(TG),total cholesterol(TC),high-density lipoprotein cholesterol(HDL-C)and low-density lipoprotein cholester⁃ol(LDL-C)were(1.38±0.98),(4.13±1.19),(1.31±0.41)and(2.25±0.77)mmol/L,respectively.The prevalence of dyslip⁃idemia was 29.72%,and the detection rates of high TG,high TC,low-HDL-C and high LDL-C were 9.73%,4.59%,19.65%and 1.99%,respectively.The prevalence of dyslipidemia was higher in men than in women(33.97%vs.25.98%;χ^(2)=1264.729,P<0.001),and the prevalence increased with age(χ^(2)=539.382,P<0.001)and body mass index(χ^(2)=3601.833,P<0.001).The prevalence of dyslipidemia was 35.48%among patients with hypertension(χ^(2)=497.251,P<0.001)and 46.07%among patients with diabetes(χ^(2)=766.142,P<0.001).There were 9059 adults with two and more abnormal blood lipid indexes(18.35%),and the detection rates of two and more abnormal blood lipid indexes were 26.50%,24.14%and 33.15%among patients with obesity,hypertension and diabetes,respectively.Conclusions The prevalence of dyslipidemia among adults in Moyu County is lower than the national level,and low-HDL cholester⁃olemia is the most common type of dyslipidemia.The prevalence of dyslipidemia is high among patients with obesity,hypertension and diabetes mellitus,in whom abnormality of multiple blood lipid indexes is measured.