摘要
原发性胆汁性胆管炎(PBC)是自身免疫性肝病之一,多数患者早期无明显临床表现,出现症状已至中晚期,尽早明确诊断及评估预后是非常必要的。抗gp210抗体对于诊断PBC及预测疾病进展有重要价值,检测该抗体可以优化PBC评分系统。本文总结评述了抗gp210抗体在PBC中的产生机制及检测的具体价值。
Primary biliary cholangitis(PBC)is one of the autoimmune liver diseases,and most patients have no obvious clinical manifesta-tions in the early stage and have reached the advanced stage when symptoms appear.Therefore,it is necessary to make a confirmed diagnosis and evaluate prognosis as early as possible.Anti-gp210 antibody is of great value in the diagnosis of PBC and the prediction of disease pro-gression,and the detection of anti-gp210 antibody can help to optimize the PBC scoring system.This article reviews the production mecha-nism and detection value of anti-gp210 antibody in PBC.
作者
张继红
李素领
ZHANG Jihong;LI Suling(The First Clinical Medical College of Henan University of Chinese Medicine,Zhengzhou 450000,China;Department of Hepatology and Spleen-Stomach,The First Affiliated Hospital of Henan University of Chinese Medicine,Zhengzhou 450000,China)
出处
《临床肝胆病杂志》
CAS
北大核心
2022年第6期1416-1419,共4页
Journal of Clinical Hepatology
基金
河南省中医药科学研究专项课题(20-21ZY1011)。
关键词
肝硬化
胆汁性
抗体
诊断
预后
Liver Cirrhosis,Biliary
Antibodies
Diagnosis
Prognosis