新生儿坏死性小肠结肠炎的危险因素研究进展

Research progress on the risk factors of neonatal necrotizing enterocolitis

新生儿坏死性小肠结肠炎(NEC)是一种高死亡率炎症性肠道疾病,表现为肠黏膜缺血、坏死、水肿等坏死性损伤,临床表现为腹胀、腹泻、呕吐、便血等,易出现肠穿孔、肠坏死、腹膜炎等并发症。本文综述了近年来有关NEC危险因素的研究进展,希望提高我们对NEC危险因素的认识,早预防早治疗,改善NEC的预后。

Neonatal necrotizing enterocolitis(NEC)is an inflammatory bowel disease associated with a substantial mortality rate.It is characterized by necrotic damage to the intestinal mucosa,including ischaemia,necrosis and oedema.Bloating,diarrhoea,vomiting and blood in the stool are among its clinical manifestations.It’s also prone to complications such as intestinal perforation,intestinal necrosis and peritonitis.In this article,recent research advances on risk factors for NEC are reviewed.It is believed that this research will contribute to a better understanding of the risk factors for NEC as well as the prognosis for NEC and we can prevent and treat it early.