复发性外阴阴道假丝酵母菌病的预防与治疗

Prevention and treatment of recurrent vulvovaginal candidiasis

复发性外阴阴道假丝酵母菌病(recurrent vulvovaginal candidiasis,RVVC)因反复发作难以根治,严重影响女性身心健康。做好RVVC预防,应寻找并纠正高危因素,鉴别感染的真菌菌种,认识混合感染。此外,研发抗真菌疫苗有望成为预防RVVC的新方法。RVVC治疗主要根据药敏试验采用敏感抗真菌药进行强化+巩固治疗,微生态调节剂、中成药等有一定的辅助治疗作用,未来有待开发新型抗真菌制剂并验证其临床疗效。

Recurrent vulvovaginal candidiasis(RVVC)is difficult to cure due to repeated attacks,which seriously affects women’s physical and mental health.To prevent RVVC effectively,high-risk factors should be found and corrected,the fungal strains should be identified,and mixed infections should be recognized.Besides,the development of antifungal vaccines is expected to be a new approach to preventing RVVC.Antifungal induction and maintenance with selective drugs according to the drug susceptibility test is the main treatment.In addition,other treatments may have certain adjuvant therapeutic effects,including microecological regulators,Chinese patent medicine,etc.In the future,new antifungal preparations need to be developed and their clinical efficacy requires verification.