2007—2016年上海市青浦区甲状腺癌发病趋势分析

Analysis of the incidence trend of thyroid cancer in Qingpu District of Shanghai from 2007 to 2016

【目的】了解2007—2016年上海市青浦区甲状腺癌的发病情况及变化趋势,为制定相关防治策略提供参考依据。【方法】利用上海市恶性肿瘤登记系统收集2007—2016年上海市青浦区居民甲状腺癌发病资料,按性别及年龄组分别计算各诊断年份的粗发病率,采用1960年世界标准人口计算年龄标化发病率,并运用Joinpoint软件计算年度变化百分比(APC),分析甲状腺癌发病率时间趋势。【结果】2007—2016年上海市青浦区甲状腺癌发病总例数为1 428例,男女性别发病比为1∶3。发病率由2007年的8.97/10万上升至2016年的52.02/10万,上升了479.93%(APC=23.60,P<0.05)。男性与女性甲状腺癌标化发病率分别为11.21/10万和32.11/10万。青浦区甲状腺癌主要集中在25~64岁,占总体发病数的88.03%。【结论】2007—2016年上海市青浦区甲状腺癌发病率上升趋势显著,高发年龄趋于年轻化且女性发病率明显高于男性,应根据其发病趋势特点制定相应的防治措施。

[Objective]To understand the incidence and change trend of thyroid cancer in Qingpu District,Shanghai from 2007 to 2016,and to provide a reference for formulating relevant prevention and treatment strategies.[Methods]The incidence data of thyroid cancer among residents in Qingpu District from 2007 to 2016 were collected using the Shanghai Malignant Tumor Registration System,and the crude incidence rate was calculated for different gender and age groups. The age-standardized incidence rate was calculated using the world standard population,and the annual percentage change(APC)was calculated using Joinpoint software to analyze the time trend of the incidence of thyroid cancer.[Results]The incidence of thyroid cancer changed from 8.97/10~5 in 2007 to 52.02/10~5 in 2016,with an increase of 479.93%(APC=23.60,P<0.05). The standardized incidence rate of thyroid cancer in men and women was 11.21/10~5 and 32.11/10~5,respectively,Male to female incidence ratio was 1∶3. Thyroid cancer in Qingpu District was mainly concentrated in the 25-64 age group,accounting for 88.03% of the total incidence.[Conclusion]From 2007 to 2016,the incidence of thyroid cancer in Qingpu District,Shanghai has a significant upward trend. The age of high incidence tends to be younger and the incidence of women is significantly higher than that of men. Corresponding prevention and treatment measures should be formulated in consideration of the discovered incidence characteristics.