丹红注射液联合心脏康复治疗在急性心肌梗死患者中的应用效果

目的探究急性心肌梗死(acute myocardial infarction,AMI)患者经皮冠状动脉介入术(percutaneous coronary intervention,PCI)术后应用丹红注射液联合心脏康复治疗的临床效果。方法纳入2018年2月至2021年3月泌阳县人民医院收治的90例AMI患者,采用随机数字表分为研究组45例及对照组45例。所有患者均行PCI治疗,术后对照组给予丹红注射液治疗,研究组于上述基础上联合心脏康复治疗。对比两组临床疗效、心肺功能[左室射血分数(LVEF)、最大代谢当量(METs)、最大摄氧量(VO_(2max)/kg)及最大氧脉搏(VO_(2max)/HR)、心排血量(CO)]、生活质量评分、不良心血管事件发生率。结果研究组治疗总有效率为95.56%,高于对照组的75.56%,差异有统计学意义(P<0.05);治疗后,研究组METs、VO_(2max)/kg、VO_(2max)/HR、LVEF及CO水平均高于对照组,差异有统计学意义(P<0.05);治疗后,研究组生活质量各项评分均高于对照组,差异有统计学意义(P<0.05);两组不良心血管事件发生率比较,差异无统计学意义(P>0.05)。结论AMI患者PCI术后采用丹红注射液联合心脏康复治疗可获得确切的临床效果,患者心肺功能得到较好的恢复,有助于提高患者的生活质量,不良心血管事件发生率较低,安全性高。

Objective To investigate the clinical effect of Danhong injection combined with cardiac rehabilitation in patients with acute myocardial infarction(AMI)after percutaneous coronary intervention(PCI).Methods A total of 90 AMI patients admitted to People's Hospital of Biyang County from February 2018 to March 2021 were enrolled and divided into study group(n=45)and control group(n=45)by random number table.All patients were treated with PCI,the control group was treated with Danhong injection,and the study group was treated with cardiac rehabilitation on the basis of the above mentioned.Clinical efficacy,cardiopulmonary function[left ventricular ejection fraction(LVEF),maximum metabolic equivalent(METs),maximum oxygen uptake(VO_(2max)/kg)and maximum oxygen pulse(VO_(2max)/HR),cardiac output(CO)],quality of life score,and incidence of adverse cardiovascular events were compared between the two groups.Results The total effective rate of the study group was 95.56%,which was higher than 75.56% of the control group(P<0.05);After treatment,the levels of METs,VO_(2max)/kg,VO_(2max)/HR,LVEF and CO in the study group were significantly higher than those in the control group(P<0.05);After treatment,the scores of quality of life in the study group were significantly higher than those in the control group(P<0.05);There was no significant difference in the incidence of adverse cardiovascular events between the two groups(P>0.05).Conclusion After PCI,patients with AMI treated with Danhong injection combined with cardiac rehabilitation can obtain exact clinical effect,and their cardiopulmonary function can be better recovered,which is helpful to improve the quality of life of patients.The incidence of adverse cardiovascular events is low and the safety is high.