康妇炎胶囊联合常规疗法治疗盆腔炎性疾病后遗症临床研究

Clinical Study on Kangfuyan Capsules Combined with Routine Treatment for Sequelae of Pelvic Inflammatory Disease

目的:观察康妇炎胶囊联合常规治疗盆腔炎性疾病后遗症(SPID)的临床疗效。方法:选择176例SPID患者作为研究对象,按照不同治疗方案分为观察组和对照组各88例。所有患者均接受左氧氟沙星、甲硝唑等常规治疗,观察组在此基础上加用康妇炎胶囊治疗。2组均连续治疗14 d,比较2组临床疗效,比较2组下腹部压痛积分、实验室检查指标评分、C-反应蛋白(CRP)水平及不良反应发生率。结果:观察组临床总有效率为94.3%,对照组为85.2%,2组比较,差异有统计学意义(P<0.05)。治疗前,2组下腹部压痛积分、实验室检查指标评分、CRP水平比较,差异无统计学意义(P>0.05);治疗后,2组压痛积分、实验室检查指标评分及CRP水平均较治疗前降低,且观察组各项指标均低于对照组(P<0.05)。治疗期间,观察组不良反应发生率为6.8%,对照组为10.2%,2组比较,差异无统计学意义(P>0.05)。结论:采用康妇炎胶囊联合常规疗法治疗SPID的疗效可靠,能明显改善机体炎症反应,减轻患者局部体征,且安全性较高。

Objective:To observe the clinical effect of Kangfuyan capsules combined with routine treatment for sequelae of pelvic inflammatory disease(SPID). Methods:A total of 176 cases of SPID patients were selected as the study subjects,and divided into the observation group and the control group according to their different treatment plans,with 88 cases in each group. Both groups were given routine treatment with levofloxacin and metronidazole,and the observation group was additionally treated with Kangfuyan capsules. Both groups were treated for 14 days. The clinical effects,scores of tenderness in lower abdomen,scores of laboratory examination,levels of C-reactive protein(CRP),and incidences of adverse reactions in the two groups were compared. Results:The total effective rate was 94.3% in the observation group and 85.2% in the control group,the difference being significant(P<0.05). Before treatment,there was no significant difference being found in the comparison of scores of tenderness and laboratory examination,and CRP levels between the two groups(P>0.05). After treatment,the scores of tenderness and laboratory examination,and CRP levels in the two groups were decreased when compared with those before treatment,and the indexes in the observation group were lower than those in the control group(P<0.05). During treatment,the incidence of adverse reactions was 6.8% in the observation group and 10.2% in the control group, there being no significant difference between the two groups(P>0.05). Conclusion: The application of Kangfuyan capsules combined with routine treatment has a reliable curative effect in treating SPID, which can significantly improve inflammatory responses in the body,and relieve local signs of patients,with high safety.