探讨血细胞检验在诊断小儿上呼吸道感染疾病中的临床意义

The Clinical Significance of Blood Cell Test in the Diagnosis of Upper Respiratory Tract Infection in Children

目的:探讨血细胞检验在诊断小儿上呼吸道感染疾病中的临床意义。方法:选择2019年1月-2020年12月某院收治的上呼吸道感染患儿84例,另外选择同期进行常规体检的健康儿童50例作为对照组。所有入选者均检测血细胞[血红蛋白(HGB)、血细胞比容(HCT)及白细胞计数(WBC)]。比较两组入选儿童HGB、HCT、WBC水平,并以临床诊断结果作为金标准,分析HGB、HCT、WBC单独与联合检测诊断上呼吸道感染的应用价值。结果:上呼吸道感染组HGB[(182.64±29.81)g/L]、HCT[(69.67±9.34)%]、WBC[(13.17±3.69)×10^(9)/L]水平均高于对照组(129.87±11.69)g/L、(46.12±5.51)%、(6.54±1.27)×10^(9)/L,差异有统计学意义(P<0.05);HGB、HCT、WBC联合诊断灵敏度(96.43%)、特异度(94.00%)、准确度(95.52%)、阳性预测值(96.43%)、阴性预测值(94.00%)均高于HGB、HCT、WBC各项单独检测,差异有统计学意义(P<0.05)。结论:HGB、HCT、WBC水平变化能够一定程度上反映上呼吸道感染患儿病情发展,3项联合诊断准确度、灵敏度、特异度更高,具有较高的应用价值。

Objective:To explore the clinical significance of blood cell test in the diagnosis of upper respiratory tract infection in children.Methods:A total of 84 children with upper respiratory tract infection admitted to a hospital from January 2019 to December 2020 were selected,and 50 healthy children who underwent routine physical examination in the hospital during the same period were selected as the control group.Blood cells hemoglobin(HGB),hematocrit(HCT),and white blood cell count(WBC)were measured in all enrolled subjects.The levels of HGB,HCT and WBC in the selected children were compared between the two groups,and the clinical diagnosis results were used as the gold standard to analyze the application value of HGB,HCT and WBC alone and in combination in the diagnosis of upper respiratory tract infection.Results:The levels of HGB(182.64±29.81)g/L,HCT(69.67±9.34)%and WBC(13.17±3.69)×10^(9)/L in the upper respiratory tract infection group were higher than those in the control group(129.87±11.69)g/L,(46.12±5.51)%,(6.54±1.27)×10^(9)/L,the difference was statistically significant(P<0.05).The sensitivity,specificity,accuracy,positive predictive value,and negative predictive value of combined diagnosis of HGB,HCT and WBC(96.43%,94.00%,95.52%,96.43%,94.00%)were higher than those of HGB,HCT,and WBC alone,and the difference was statistically significant(P<0.05).Conclusion:The changes of HGB,HCT and WBC levels can reflect the disease development of children with upper respiratory tract infection to a certain extent,and the three combined diagnosis has higher accuracy,sensitivity and specificity,with high application value.