全程营养追踪管理对宫颈癌放化疗患者的影响

Effect of whole-course nutritional tracking management on patients with cervical cancer radiotherapy and chemotherapy

目的探究全程营养追踪管理对宫颈癌放化疗患者免疫功能、营养状态及生活质量的影响。方法选取医院2019年4月—2021年6月收治的100例宫颈癌放化疗患者为研究对象,按照组间基本特征具有可比性的原则分为观察组与对照组,每组50例,对照组在放化疗期间进行常规护理,观察组在此基础上实施全程营养追踪管理,比较两组患者干预前后营养相关指标、免疫相关指标的变化,评估患者干预前后生活质量的差异。结果干预前,两组患者免疫球蛋白IgA、IgG、IgM以及CD3^(+)和CD4^(+)等免疫功能指标、血红蛋白、血清白蛋白和前清蛋白等营养指标以及生活质量评分比较差异均无统计学意义(P>0.05);干预3个月后,观察组免疫球蛋白IgA、IgG、IgM以及CD3^(+)和CD4^(+)等免疫功能指标的水平值均高于对照组,组间比较差异有统计学意义(P<0.05);干预3个月后,观察组血红蛋白、血清白蛋白和前清蛋白等营养指标水平均高于对照组,组间比较差异有统计学意义(P<0.05),观察组功能领域各维度评分均高于对照组,症状领域评分低于对照组,各指标比较差异有统计学意义(P<0.05)。结论对宫颈癌放化疗患者实施全程营养追踪管理,可有效提高免疫功能,改善营养状况,提升生活质量。

Objective To explore the effects of whole-course nutritional tracking management on immune function,nutritional status and quality of life in patients with cervical cancer undergoing radiotherapy and chemotherapy was as the study subject.Methods A total of 100 patients with cervical cancer radiotherapy and chemotherapy who were admitted to the hospital from April 2019 to June 2021 were selected as the study objects.According to the principle of comparability of basic characteristics between groups,they were divided into observation group and control group,with 50 cases in each group.The control group received routine nursing during the period of radiotherapy and chemotherapy,and the observation group implemented the whole-process nutrition tracking management on this basis.The changes of nutrition-related indicators and immune-related indicators before and after the intervention were compared between the two groups,and the differences in the quality of life of the patients before and after the intervention were evaluated.Results Before the intervention,there were no significant differences in immunoglobulin IgA,IgG,IgM,immune function indexes such as CD3^(+) and CD4^(+) ,nutritional indexes such as hemoglobin,serum albumin and prealbumin,and quality of life scores between the two groups(P>0.05).After 3 months of intervention,the levels of immunoglobulin IgA,IgG,IgM,CD3^(+) and CD4^(+) in the observation group were higher than those in the control group,and the differences between the groups were statistically significant(P<0.05).After 3 months of intervention,the levels of hemoglobin,serum albumin and prealbumin in the observation group were higher than those in the control group,and the differences between the groups were statistically significant(P<0.05).The scores ofeach dimension in the functional domain of the observation group were higher than those of the control group,and the score of the symptom domain was lower than that of the control group,and the differences in each index were statistically significant(P<0.05).Conclusion The whole-process nutrition tracking management for cervical cancer patients undergoing radiotherapy and chemotherapy can effectively improve immune function,improve nutritional status,and improve quality of life.