基于隐结构模型探析后溪穴古代配伍规律

Analysis on combination regularities of Houxi(SI3)in ancient times of China based on latent structure model

目的:以后溪穴为例,初探隐结构模型分析腧穴古代配伍规律的可行性与应用价值。方法:以《中华医典》(第五版)为检索源,构建后溪配伍腧穴数据库,运用Lantern 5.0软件对高频腧穴开展隐结构分析。结果:共纳入医籍26部,条文240条。高频配伍腧穴为申脉、合谷、前谷和风池等46穴。对高频腧穴建模得到12个隐变量及24个隐类,模型评分-2170.68,将Y0至Y11综合聚类得到7类穴组。阳经的配伍比重高于阴经;重视五输穴、交会穴等特定穴叠效配伍;配穴集中分布于上肢、下肢和头面颈项等部位;围绕后溪将功效延伸至舒筋活络、清热疏风、明目开窍和消肿止痛等四方面。结论:基于隐结构模型分析腧穴配伍规律切实可行,综合聚类厘定主次配穴,揭示出主、次穴的共性规律与逻辑递进关系,有助于为教学、临床和科研提供借鉴。

Objective To explore the feasibility and application value of combination regularities of acupoint Houxi(SI3)in Chinese ancient times based on latent structure model.Methods Relevant articles about SI3 for treating various diseases with acupuncture,moxibustion,acupoint application,etc.were mainly searched from book Chinese Medical Classics(5 th edition),followed by establishment of a Database of Houxi Acupoint Recipes.The Lantern 5.0 software was used to construct and analyze the latent structure model of high-frequently-used acupoints.Results A total of 46 high frequently-used acupoints contained in 240 articles of 26 medical books were collected.The top 7 acupoints are Shenmai(BL62),Hegu(LI4),Qiangu(SI2),Fengchi(GB20),Jianshi(PC5),Wangu(SI4)and Quchi(LI11)in sequence.After modeling the 46 high-frequently used adjunct acupoints,12 latent variables(Y0-Y11)and 24 latent classes were obtained by setting the cumulative coverage threshold ratio to be 95%.According to the Bayesian information criterion(BIC)measure,the model score was-2170.68 points.Seven comprehensive clustering models were summarized up according to the latent structure.Compared with the yin meridians,the yang meridians played a more significant role.The multiple combinations of SI3 with specific acupoints provided a reference for clinical practice.The supplementary acupoints mainly distribute in the upper and lower limbs,head,face,neck,etc.and the SI3 acupoint recipes function mainly in dredging and activating meridians and collaterals,clearing away pathologic heat and wind,improving eyesight,and relieving swelling and pain.Conclusion The latent structure model is applicable in analysis of the regularities of SI3 acupoint combination for treating some diseases.Comprehensive clustering is employed to determine the primary acupoint SI3 and adjunct acupoint matching,revealing the common regularity and logical progressive relationship between the primary and secondary points,which may be helpful for teaching,clinical and scientific research.