摘要
淋巴管作为循环系统的重要组成部分之一,具有调节机体体液稳态,协助免疫监视和肠道脂质吸收等重要作用。淋巴管新生是机体生理和病理过程中维持脉管系统结构和功能正常的重要手段,淋巴管新生调控对于防治肿瘤、心血管等诸多疾病有着潜在的临床转化意义;淋巴回流功能则与关节炎症等疾病发病机制关系密切。在循环系统中,相较于中医药调控血管相关疾病的发病机制已取得很大进展,近年来对于淋巴管的研究则明显相对滞后。本文从中医药作用于淋巴管新生及回流功能角度对这一领域的研究进展作一综述,以期为临床上中医药治疗相关疾病提供新的思路与方法。
As one of the important components of the circulatory system, lymphatic vessels have important functions such as regulating the homeostasis of body fluids, assisting in immune surveillance and intestinal lipid absorption.Lymphangiogenesis is an important means to maintain the normal structure and function of the vasculature in the physiological and pathological processes of the body. The regulation of lymphangiogenesis has potential clinical translational significance for the prevention and treatment of tumors, cardiovascular and many other diseases;the function of lymphatic drainage is related to joint inflammation and other diseases. In the circulatory system, compared with the in-depth pathogenesis of vascular-related diseases regulated by Traditional Chinese Medicine(TCM), the research on lymphatic vessels has been relatively lagging behind in recent years. This paper reviewed the research progress in the field of TCM on lymphatic angiogenesis and drainage function, in order to provide some new ideas for the TCM’s clinical treatment of related diseases.
作者
周茂琳
王怿
周嫦
彭珑萍
梁倩倩
王佑华
Zhou Maolin;Wang Yi;Zhou Chang;Peng Longping;Liang Qianqian;Wang Youhua(Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200032,China;Key Laboratory of Theory and Therapy of Mucles and Bones,Ministry of Education of China,Shanghai 200032,China)
出处
《世界科学技术-中医药现代化》
CSCD
北大核心
2022年第2期802-809,共8页
Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology
基金
国家自然科学基金委员会面上项目(81873264):基于VEGFC/D-VEGFR3/NRP2轴通路探讨扩张型心肌病心脏淋巴管生成障碍机制及中药扩心方干预作用的研究,负责人:王佑华
国家自然科学基金委员会优秀青年科学基金项目(81822050):中医药防治关节炎的应用基础研究(中医药调控淋巴管系统功能治疗关节炎),负责人:梁倩倩
国家自然科学基金委员会重点国际合作与交流项目(81920108032):蠲痹汤调节滑膜淋巴管内皮细胞功能治疗类风湿关节炎的研究,负责人:梁倩倩。
关键词
淋巴管
淋巴系统
淋巴管新生
淋巴回流功能
中医药
Lymphatic vessels
Lymphatic system
Lymphangiogenesis
Lymphatic drainage function
traditional Chinese medicine(TCM)