腹腔镜手术治疗结肠癌和炎症性肠病的临床效果分析

Clinical Effect of Laparoscopic Surgery in the Treatment of Colon Cancer and Inflammatory Bowel Disease

目的:针对腹腔镜手术治疗结肠癌和炎症性肠病的临床效果进行具体分析,以此为参考依据。方法:回顾2018年2月~2020年6月在本院就医的96例结肠癌和炎症性肠病患者作为研究对象,并进行随机分组,分为对照组与观察组。对照组选择用开腹手术进行治疗,观察组则选择采用腹腔镜手术进行治疗,对试验数据进行统计分析,将两组手术相关指标、免疫功能指标、临床效果、并发症发生情况、局部复发情况进行对比。结果:与对照组比较,观察组手术时间、术后首次排气时间、住院时间明显较短,术中出血量明显较少,CD3^(+)、CD4^(+)、CD4^(+)/CD8^(+)、总有效率明显较高,并发症发生率明显较低,差异存在统计学意义(P<0.05)。结论:选择运用腹腔镜手术治疗结肠癌和炎症性肠病疗效更好,患者的手术中出血量相对较少,术后肠功能恢复普遍较快,对免疫功能的不良影响也相对较小。

Objective:To analyze the clinical effect of laparoscopic surgery in the treatment of colon cancer and inflammatory bowel disease.Methods:96 patients with colon cancer and inflammatory bowel disease treated in our hospital from February 2018 to June 2020 were reviewed and randomly divided into control group and experimental group.The methods used in the control group and the experimental group were as follows:the control group chose laparotomy for treatment,and the experimental group chose laparoscopic surgery for treatment.The experimental data were statistically analyzed,and the operation related indexes,immune function indexes,clinical effects,complications and local recurrence of the two groups were compared.Results:Compared with the control group,the operation time,the first postoperative exhaust time,the length of hospital stay,the amount of intraoperative bleeding,the total effective rate of CD3^(+),CD4^(+),CD4^(+)/CD8^(+)and the incidence of complications in the experimental group were significantly shorter,and the difference was statistically significant(P<0.05).Conclusion:Laparoscopic surgery is more effective in the treatment of colon cancer and inflammatory bowel disease.The amount of bleeding in the operation is relatively less,the recovery of intestinal function is generally faster,and the adverse effect on immune function is relatively small.