呼吸机在ICU急性呼吸窘迫综合征患者治疗中的临床效果

The Clinical Effect of Ventilator in the Treatment of ICU Patients with Acute Respiratory Distress Syndrome

目的:分析呼吸机在ICU急性呼吸窘迫综合征患者治疗中的临床效果。方法:选取2017年6月~2020年6月本院ICU收治的110例急性呼吸窘迫综合征患者为研究对象,基于治疗过程中是否应用呼吸机将其分为两组。对照组给予常规抗感染治疗,研究组在常规抗感染治疗基础上应用呼吸机,选择同步间歇指令通气及呼气末正压通气模式进行治疗。观察两组患者治疗前后的血气指标、肝肾功能指标和病死率。结果:治疗前两组患者各项血气指标和肝肾功能指标差异均不显著(P>0.05),治疗后研究组患者心率、呼吸频率、血氧饱和度、血氧分压(mmHg)、中心静脉压等各项血气指标均显著优于对照组(P<0.05),治疗后研究组患者天冬氨酸氨基转移酶、丙氨酸氨基转移酶、血尿素氮、血清肌酐等各项肝功能和肾功能指标均显著优于对照组(P<0.05)。研究组死亡率为0(0/55),低于对照组的3.64%(2/55),但组间没有显著差异(P>0.05)。结论:对ICU急性呼吸窘迫综合征患者在治疗中应用呼吸机进行辅助治疗,可以改善治疗效果。

Objective:To analyze the clinical effect of ventilator in the treatment of ICU patients with acute respiratory distress syndrome.Methods:110 patients with acute respiratory distress syndrome in ICU of our hospital from June 2017 to June 2020 were selected as the research objects,and they were divided into two groups based on whether the ventilator was used.The control group was given routine anti infective treatment,while the study group was treated with ventilator on the basis of routine anti infective treatment,and selected synchronous intermittent mandatory ventilation and positive end expiratory pressure ventilation.The blood gas index before and after treatment and mortality of the two groups were observed.Results:Before treatment,there was no significant difference in various blood gas indexes and liver and kidney function indexes between the two groups(P>0.05).After treatment,the heart rate,respiratory rate,blood oxygen saturation,blood oxygen partial pressure(mmHg),central venous pressure and other blood gas indexes of the study group were significantly better than those of the control group(P<0.05).After treatment,aspartate aminotransferase,alanine aminotransferase,blood urea nitrogen Serum creatinine and other indicators of liver and renal function were significantly better than those in the control group(P<0.05).The mortality of the study group was 0(0/55),which was lower than 3.64%(2/55)of the control group,but there was no significant difference between the two groups(P>0.05).Conclusion:The application of ventilator in the treatment of patients with acute respiratory distress syndrome in ICU can improve the therapeutic effect.